Cancer Eating garlic, onions reduces risk of endometrial cancer
By David Liu Ph.D.
Nov 28, 2008 - 12:30:33 PM
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Friday Nov 28, 2008 (foodconsumer.org) -- A new study published in the Nov 2008 issue of Public
Health Nutrition suggests that eating allium vegetables like garlic and onions
may reduce the risk of endometrial cancer.
The study found that those who consumed high amounts of
garlic and onion reduced their risk of endometrial cancer by as much as 38 and
60 percent respectively compared to those who use lower amounts of the allium
vegetables.
Endometrial cancer forms in the tissue lining the uterus.
Most endometrial cancers are adenocarcinomas. The disease is diagnosed in
40,000 women and kills more than 7,000 in the Unites States each year,
according to the National Cancer institute.
Early Chinese studies have showed the similar associations.
But the current study sought to examine the possible protective effect in a
Western population.
For the study, Galeone C and colleagues from
Istituto di Ricerche Farmacologiche 'Mario
Negri' in Milan, Italy analyzed data from a multi-centre case-control study of
454 endometrial cancer cases and 908 controls who were admitted to the same
hospital for acute, non-neoplastic conditions.
The participants were interviewed by trained professionals
using a validated and reproducible food frequency questionnaire.
The researchers found that compared with non-users, those
who used less
than 2 portions of onions
per week were 6 percent less likely to develop endometrial cancer and those who
ate more than or equal to 2 portions per week were 60 percent less likely to
have the disease.
There was an inverse correlation between eating onions
and risk of endometrial cancer.
One
portion of onions (80 grams) per week was associated with a 19 percent
reduction in risk of the disease.
The researchers also found that those who used moderate
amounts of garlic weekly were 11 percent less likely to have endometrial cancer
while those who used high amounts of garlic were at a 38 percent reduced risk
of the disease.
The authors said in their report that "Our study
found a moderate protective role of allium vegetables on the risk of
endometrial cancer."
Source:
Public Health Nutr. 2008 Nov 6:1-4.
Allium vegetables intake and endometrial cancer risk.
Galeone C, Pelucchi C, Dal Maso L, Negri E, Montella M,
Zucchetto A, Talamini R, La Vecchia C.
1Istituto di Ricerche Farmacologiche 'Mario Negri', Via
La Masa 19, I-20156 Milan, Italy.