Dietary factors and type 2 diabetes mellitus

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Below is a short summary of recent reports on how dietary factors may help prevent or treat type 2 diabetes mellitus.

I. Sluijs of University Medical Center Utrecht in Utrecht, The Netherlands and colleagues published a study in Journal of Nutrition suggesting that having a high serum level of uric acid may increase risk of type 2 diabetes mellitus.  Eating fructose can increase serum uric acid.

A. Ahangarpour at Diabetes and Physiology Research Centers, Jundishapur University of Medical Sciences in Ahvaz, Iran and colleagues reported in Iran Journal of Medical Science that urtica dioica leaf extract may be used to help improve the condition of diabetes mellitus, that is, this extract can decrease serum glucose and insulin.
 
M. C. Castro of CENEXA, Centro de Endocrinología Experimental y Aplicada, UNLP-CONICET LA PLATA, Centro Colaborador OPS/OMS in La Plata, Argentina and colleagues reported in Biochim Biophys Acta that alpha-lipoic acid supplemented diet prevented high serum insulin, blood sugar and insulin resistance. 

E. Müllner of University of Vienna, Austria and colleagues published a study in Molecular Nutrition and Food Research showing that subjects with diabetes mellitus who ate 300 grams of vegetables and 25 mL of PUFA rich plant oil per day for 8 weeks or two months increased serum levels of antioxidants and reduced glycated hemoglobin or HbA1c, which is a biomarker indicating the severity of diabetes, and DNA strand breaks.  PUFA refers to polyunsaturated fatty acids.
 
In International Journal of Current Biomedical and Pharmaceutical Research, Rosin Day and Sapna Smith La of Bheem Rao Ambedkar Medical College, Gorkhpur reported that vitamin E and vitamin C supplements can help reduce oxidative stress in postmenopausal women with type 2 diabetes mellitus.

K.S. Kim and colleagues reported a study in Experimental and Molecular Medicine that shows a diet with 2% taurine supplemented may help patients with type 2 diabetes mellitus better manage their serum glucose and cholesterol.

W. Bao and colleagues reported in BMC Medicine that the highest intake of heme iron were at 33 percent increased risk for diabetes mellitus type 2, compared to those who had the lowest intake. Heme iron is found in red meat.
 
N. Ibarrola-Jurado at Universitat Rovira i Virgili in Reus, Spain and colleagues published a study in American Journal of Clinical Nutrition that shows high dietary intake of phylloquinone or vitamin k1 was associated with a 50 percent reduced risk of developing diabetes type 2 in people at high risk of cardiovascular disease.
 
Kylie Kavanagh of Wake Forest University School of Medicine in Winston-Salem, NC and colleagues reported in the journal of Obesity that monkeys having had dietary intake of trans fat in a dose of about 8% of energy for six years gained significant amounts of weight with increased intra-abdominal fat deposition and impaired glucose metabolism. Both trans fat and saturated are found implicated in type 2 diabetes mellitus.

S.K. Jain of LSU Health Sciences Center in Shreveport, LA  reported in Canadian Journal of Physiology and Pharmacology that L-cysteine supplements, which are relatively cheap could be used as an adjuvant therapy for type 2 diabetes mellitus.    Both in animals and people with type 2 diabetes mellitus, cysteine-rich whey protein has been demonstrated to be able to improve glucose metabolism.
 
Kate Marsh whose affiliation is not immediately clear published a report in Diabetes Management saying that people eating a vegetarian diet were at reduced risk for diabetes mellitus type 2.   Of course a vegan diet can be better at preventing diabetes.

M. Vafa of Department of Nutrition, Tehran University of Medical Sciences in Tehran, Iran and colleagues reported in International Journal of Preventive Medicine that cinnamon can improve a range of metabolic parameters associated with type 2 diabetes mellitus and metabolic syndrome.

G.J. van Woudenbergh of InterAct Consortium and colleagues reported a review study in PLoS One that suggests that  those drinking less than 4 cups of tea per day was associated with 7 percent reduced risk of type 2 diabetes mellitus, compared with those who did not drink any.

Researchers of Srinakharinwirot University in Bangkok Somlak Chuengsamarn, MD and colleagues reported in the journal Diabetes Care that eating curry or taking curcumin supplements helps reduce risk of type 2 diabetes mellitus. 

In Cardiovascular Daibetology, N.M. Al-Daghri of King Saud University in Kingdom of Saudi Arabia and colleagues found patients with type 2 diabetes taking vitamin D supplements for 18 months lowered low density lipoprotein cholesterol by 18 percent and total cholesterol by 9 percent among other benefits.

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