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Hypertension plus type 2 diabetes more likely lead to cardiovascular disease

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By David Liu, PHD

Saturday Nov 3, 2012 (foodconsumer.org) -- J. Segura of Hospital Universitario 12 de Octubre, Madrid, España and colleagues published a study recently in  Medicica and Clinica saying that patients with both hypertension and type 2 diabetes were more likely than those with only hypertension to develop cardiovascular disease and other medical conditions.

The cross sectional study was intended to examine how type 2 diabetes in hypertensive patients affects the risk of target organ damage (TOD) and cardiovascular disease in reference to those who had hypertension, but no type 2 diabetes.

The study involved 4,725 hypertensive patients at a mean age of 64 years with 2608 having type 2 diabetes and 2117 having three or more cardiovascular risk factors. 

Hypertensive patients with type 2 diabetes tended to be older and more likely to be severely obese.   And these patients were more likely to have micro- any macroalbuminuria, renal failure or kidney failure, left ventricular hypertrophy, atherosclerotic plaques in carotid arteries and cardiovascular disease, compared with those non-diabetic hypertensive patients with three or more cardiovascular risk factors (CVRF).

Statistical analysis showed that the risk of target organ damage or established cardiovascular disease were independently associated with the presence of type 2 diabetes.

The researchers concluded "Hypertensive patients with type 2 diabetes have a higher prevalence of LOD and CVD compared to nondiabetic hypertensive patients with 3 or more CVRF. Although both situations are included in the high cardiovascular risk stratum, it would be expected an increased incidence of cardiovascular complications in hypertensive diabetic patients."

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