More genes linked to breast cancer risk
UK Researchers found five more genes associated with breast cancer risk explaining why some women have a family history of the disease.
The researchers at Cambridge University scanned the entire genetic code of about 4,000 patients with a family history of breast cancer and 24,000 women with and without the disease.
They found five DNA loci on the human genome linked to a family history of breast cancer.
The finding brings to 18 the number of common genetic variations linked to breast cancer including BRCA1 and BRCA2.
Inherited faults are believed to raise a small risk, about one in 20 of all breast cancer cases.
The study was funded by Cancer Research UK and led by Dr Douglas Easton of the University of Cambridge and colleagues. The results are published in Nature.
Breast cancer is diagnosed in more than 170,000 women each year in the United States and the disease kills about 50,000 annually in the country.
David Liu



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