Pomegranate juice may help prevent prostate cancer
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Pomegranate juice may help prevent migration of prostate cancer cells and potentially inhibit the metastasis of prostate cancer to the bone, according to a study presented at American Society of Cell Biology's 50th annual meeting in Philadelphia.
The study led by Manuela Martins-Green, Ph.D. and colleagues at the University of California in Riverside (UCR) identified the active components in pomegranate juice and planned to do in vivo tests to see if two compounds could be used as preventatives against prostate cancer.
The pomegranate juice was provided by Pom Wonderful, which was sued by the Federal Trade Commission allegedly for making false and misleading claims about the juice's effect on health.
One 2006 study by the same authors showed drinking eight-ounce glass of pomegranate juice reduced the prostate-specific antigen levels.
Previous studies by Dr. Martins-green and colleagues tested a standardized concentration of pomegranate juice on two lines of cultured prostate cancer cells that were resistant to testosterone. Resistance to the hormone means the cancer cells have a strong potential to migrate to other organs.
The researchers found pomegranate juice can not only promote death of prostate cancer cells, but also increased cell adhesion and reduced migration of the cancer cells that had not died.
The identified compounds included phenylpropanoids, hydrobenzoic acids, flavones and conjugated fatty acids.
Jimmy Downs
Photo credit: wikipedia
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