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Type 1 diabetes mellitus linked to worse pregnancy outcomes

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By Jimmy Downs

Thursday Nov 15, 2012 (foodconsumer.org) -- Women with type 1 diabetes mellitus have a high risk of adverse outcomes of pregnancy, according to a study in Irish Journal of Medical Science.

R. Al-Agha and colleagues compared the outcomes of pregnancy in all type 1 diabetes mellitus patients with women who were not diabetic and found pregnant women with type 1 diabetes mellitus had a higher risk of spontaneous abortion, perinatal mortality and having foetal macrosomia.

Exactly, the researchers compared pregnancy outcomes in 6000 type 1 diabetes mellitus pregnant women and 142,498 non diabetic pregnant women who attended at outpatients clinics in three university teaching hospitals in Dublin between 1995 and 2006.

Among pregnant women with type 1 diabetes mellitus, the spontaneous abortion rate was 15%, perinatal mortality rate 3.3% and fetal macrosomia rate 29%, compared to 8%, 0.9% and 16%, respectively in pregnant women without diabetes mellitus.

The researchers concluded "Pregnancy outcomes in T1DMP (type 1 diabetes mellitus pregnancies) remain worse than in the general population despite management of T1DMP in combined obstetric/diabetes clinics in a single centre using similar management protocols. These outcomes in our study population of T1DMP in Dublin appear better than some previously reported studies."

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