This humble veggie may help prevent prostate cancer
By David Liu
Wednesday May 30, 2012 (foodconsumer.org) -- Eating cruciferous vegetables may help prevent prostate cancer, according to a new study in the Biochimica et Biophysica Acta - Molecular Cell Research released online 25 May 2012.
Specifically, the study shows that sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells, which suggests that sulforaphane (SFN) may have an anticancer effect against prostate cancer.
Aleksandra Wiczk of University of Gda?sk in Gda?sk, Poland and colleagues, the authors of the report, said that sulforaphane found in cruciferous plants has been found for long to be able to fight prostate cancer cells in vitro and animals.
The authors said sulforaphane "inhibits cell proliferation, induces apoptosis, autophagy, and sensitizes cancer cells to therapies."
The authors demonstrated in their laboratory study that "SFN inhibits protein synthesis in PC-3 cells in a dose- and time-dependent manner which is accompanied by a decreased phosphorylation of mTOR substrates."
Prostate cancer is diagnosed in about 200,000 men in the United States each year, and the disease kills about 37,000 men each year in the country, according to the National Cancer Institute.
The following is a list of cruciferous vegetables
Chinese broccoli (gai-lan)
Rapini (broccoli rabe)
chinese cabbage, napa cabbage
turnip root; greens
wrapped heart mustard cabbage
mustard seeds, brown; greens
mustard seeds, white
mustard seeds, black
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