Drinking coffee may cut endometrial cancer risk
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By David Liu PHD
Sunday Jan 09, 2012 (foodconsumer.org) -- Drinking coffee may help reduce risk of endomettrial cancer, according to a study published in 2011 in International Journal of Cancer.
The study led by Youjin Je and Edward Giovannucci of Harvard School of Public Health in Boston, MA showed that women drinking the highest amounts of coffee was up to 29 percent less likely to develop endometrial cancer, compared with those who drank the lowest amounts.
Ye and Giovannucci pooled data from 16 studies (16 case-control and 6 cohort studies ) on coffee intake with 6,628 endometrial cancer cases for a meta-analysis.
The authors found both case-control studies and cohort studies led to a similar finding - both revealed that drinking highest amounts of coffee was correlated with about 30 percent reduced risk for breast cancer.
The association seemed to be stronger in the three Japanese studies, which showed that drinking highest amounts of coffee was associated with 60 percent reduced risk, while five U.S. and canadian stduies showed a 31 percent reduction and eight European studies found a 21 percent reduction in the risk for breast cancer.
An increment of one cup of coffee per day was linked to a 8 percent reduction in the risk.
The researchers concluded "our findings suggest that increased coffee intake is associated with a reduced risk of endometrial cancer, consistently observed for cohort and case-control studies. More large studies are needed to determine subgroups to obtain more benefits from coffee drinking in relation to endometrial cancer risk."
Keywords: coffee; dietary factors; hyperinsulinemia; endometrial cancer; observational study; meta-analysis
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