Fast food breakfast linked to inflammation
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A new study led by University of California at Davis suggests eating high fat meals like fast food breakfast can lead to inflammation.
Eating high fat meals boost blood fat called triglycerides, which in the form of triglyceride-rich lipoprotein (TGRL) can cause inflammation of the endothelium in individuals with existing low grade inflammation or in those who are vulnerable for inflammation.
"The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall," wikipedia states.
The study was released online in the journal American Journal of Physiology - Heart and Circulatory Physiology.
For the study, Dr. Anthony Passerini and colleagues enlisted 61 people with different fasting triglyceride levels and different size waistlines.
The researchers measured triglycerides after the subjects ate a typical fast food breakfast consisting of two breakfast sandwiches, hash browns and orange juice.
They found the size of triglyceride-rich lipoprotein or TGRL varied with an individual's triglyceride level and waistline size.
Specifically, they found subjects with both a big waistline (over 32 inches) and high triglyceride levels were at higher risk of inflammation because the size of TGRL was larger and the particles were more easily bound to the endothelial cells causing inflammation when responding to an immune chemical trigger.
The researchers said the findings suggest people with existing low grade inflammation may be more prone to endothelial dysfunction after eating high fat meals and facing a triglyceride spike in the blood.
At particularly higher risk of atherosclerosis or hardening of the arteries, which leads to heart disease and stroke, may be those who have repeated episodes of inflammation, according to the researchers.
By David Liu and editing by Aimee Keenan-Greene
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