Fructose raises risk for kidney disease, hypertension
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By David Liu, Ph.D.
Saturday, Nov 19, 2011 (foodconsumer.org) -- Eating too much fructose may cause a series of diseases including fatty liver, insulin resistance or diabetes, dyslipidemia, hypertension and kidney disease, according to a report in the Nov 2011 issue of International Journal of Nephrology.
In the report, Marek Kretowicz of Nicolaus Copernicus University in Torun Porland and colleagues reviewed 62 studies and concluded that studies suggest that excessive fructose intake may be one of the causes for the current epidemic of obesity, diabetes and cardiorenal disease.
Fructose is a monosaccharide present in sucrose (beet sugar, cane sugar etc), high fructose corn syrup (hfcs), honey and fruits.
The researchers cited studies as suggesting that not all fructose sources are the same. Not all sources of fructose cause diabetes, kidney disease and cardiovascular disease.
The researchers said natural sources of fructose such as fruits are rich in beneficial nutrients like antioxidants, vitamin C or ascorbic acid, polyphenols, potassium, and fiber that may counter the adverse effect of fructose. Previous studies found fructose intake was not correlated with increased risk of high blood pressure or hypertension in a population in which much of the fructose intake came from fruits. However, the association was found significant when the fructose from fruits was excluded.
According to the report, fructose can cause fatty liver and glycogen accumulation, insulin resistance and islet dysfunction, obesity, hypertension and vascular disease, and kidney disease.
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