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Meat, vegetable oils may boost risk of inflammatory bowel disease

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By David Liu, Ph.D.

Monday Nov 07, 2011 (foodconsumer.org) -- A review article released in a recent issue of the journal Digestive and Liver Disease found a diet high in protein, particular animal protein is associated with increased risk of inflammatory bowel disease and relapses.

The review led by Vibeke Andersen of Viborg Regional Hospital, Viborg, Denmark and coleagues also found omega-6 polyunsaturated fatty acids found high in vegetable oils like corn oil and soybean oil may predispose to ulcerative colitis while omega-3 fatty acids found high in fish including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) may protect against the condition.

The findings were based on a review of articles on diet and risk of inflammatory bowel disease, which were reported in the Pubmed, Medline and Cochrance Library.

The researchers did not find though any association between intake of dietary fibers, sugar, macronutrients, total energy, vitamin D, E, C carotene and retinol or vitamin A on the risk of ulcerative colitis.

It remains unknown whether intake of fruits, vegetables or food microparticles like titanium dioxide and aluminium silicate because of no prospective data were available for the review.

Aluminum salts have been found to have adverse effects on neurological health while nanoparticles like titanium dioxide may increase the odds of mutation and increase risk of cancer development, early studies suggest. The toxicity of nanoparticles may depend on their sizes.

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine of which ulcerative colitis is one of the major conditions. IBD is rarely fatal, but it does reduce the quality of life.

Symptoms of IBD include "abdominal pain, vomiting, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis, weight loss and various associated complaints or diseases like arthritis, pyoderma gangrenosum, and primary sclerosing cholangitis. Diagnosis is generally by colonoscopy with biopsy of pathological lesions," according to wikipedia.
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