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Herbal remedies interfere with drugs for heart disease

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Patients who are using drugs indicated to treat or prevent heart disease should by all means avoid using herbal remedies, as there can be some dangerous interactions between the two, according to a study published in the February 9, 2010, issue of the Journal of the American College of Cardiology. 

In the U.S., as many as 15 million people are reported to use herbal remedies or high doses of vitamins. These dietary supplements are natural, but not necessarily safe, according to the study authors.  They can either reduce or increase the potency of the drugs indicated for treatment of heart disease, leading to bleeding or serious cardiac arrhythmia. 

The herbal remedies that may cause problems in patients taking drugs for heart disease include St. John's wort, gingko biloba, garlic and even grapefruit juice among others, said Arshad Jahangir, M.D., Professor of Medicine and Consultant Cardiologist, Mayo Clinic Arizona and colleagues. 

The herbal supplements can be particularly risky for elderly people who have co-morbidities, take multiple medications and are at higher risk of bleeding, the researchers said. 

Some examples of the drug-herb interactions include: 

St. John's wort can reduce the effectiveness of heart medications and lead to increased risk of arrhythmia and high blood pressure or cause an increase in blood cholesterol. 

Both Garlic and Ginkgo Biloba may increase the risk of bleeding in people who take warfarin (coumadin) or aspirin.  

Grapefruit juice is known to boost the potency of certain drugs to dangerous levels.



By Jimmy downs and editing by Denise Reynolds



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Subscribe to comments feed Comments (3 posted):

Jhoane on 02/02/2010 12:33:15
As an herbalist, I've studied herbs for years. Of course certain herbs can increase/potentiate certain drug's effectiveness. This is not a danger when working with the doctor and medication levels. This information does not need raise alarms, just awareness. Common sense dictates, for instance, that when an herb may thin blood a little, like gingko can, then blood thinning medications may 'work better', and levels need to be watched and adjusted accordingly. The benefits from whole herbs is that they have micro-nutrients that help build health in the structure and function in the body, which drug medications cannot do - they are designed for specifically targeted symptom needs.
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Mark H on 02/02/2010 12:50:06
I don't doubt that herbs can increase or decrease the potency of medications. I do doubt the medical community. How can they release all these studies that say "herbs don't work", "don't help","they're ineffective", etc... Then turn around in other studies and claim they are so effective that they could affect your medication! All these studies sure have the tainted taste of the pharmaceutical industry!
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Review on 05/10/2010 13:22:28
Several herbal medicines have been shown to interfere with blood measurements of medications, which are necessary to ensure that a person is receiving the appropriate dose of the particular drug.
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