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Could Coenzyme Q10 boost breast cancer risk?

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A new study published online July 28 in Cancer Epidemiology, Biomarkers and Prevention showed that women with highest concentrations of plasma coenzyme Q10 were more than twice as likely as those who had lowest amounts to be diagnosed with breast cancer.

Coenzyme Q10 or coQ10 is a component of the mitochondrial electron transport chain and acts as an important cellular antioxidant.  Decreased levels of coQ10 have been found in women with breast cancer, according to the background information in the study report.

The current case-control study led by Weiwen Chai at University of Hawaii in Honolulu and colleagues was meant to examine the association between plasma CoQ10 levels and postmenopausal breast cancer risk.

Chai et al. compared 160 postmenopausal women with breast cancer and 289 controls who were matched on age, sex, ethnicity, study location, hormone replacement therapy use, date, and time of specimen collection, and hours of fasting.

The researchers found serum CoQ10 levels were positively associated with breast cancer risk. When women diagnosed within one year of blood draw were excluded, those with the highest levels were 126 percent more likely to be diagnosed with breast cancer.

They concluded that "Higher CoQ10 levels in postmenopausal women may be associated with increased breast cancer risk."

It should be noted that having higher levels of plasma CoQ10 may not necessarily the cause of the higher risk of breast cancer.  It is possible that women diagnosed with breast cancer may take some vitamin supplements, which would boost the serum level of this nutrient.

In any case, this study does not have the final say about the safety of CoQ10.  According to the Linus Pauling Institute, up to 1200 mg per day of coenzyme Q10 is considered safe.

CoQ10 has been found to benefit a range of health conditions including Parkinson's disease, Huntington's disease, diabetes mellitus, hypertension, vascular endothelial function, angina pectoris, myocardial infarction and cardiac surgery, and congestive heart failure.

Breast cancer is expected to be diagnosed in one in eight women in the United States in their lifetime.  The disease will be diagnosed in more than 175,000 women in 2010 and kill about 50,000, according to the National Cancer Institute.

More reports will be published here on foodconsumer.org in the national Breast Cancer Institute  to help readers better understand breast cancer and how to prevent the disease.


Jimmy Downs

(Send your news to foodconsumer.org@gmail.com, Foodconsumer.org is part of the Infoplus.com ™ news and information network)

Subscribe to comments feed Comments (3 posted):

juicy couture outlet online on 10/16/2010 03:59:33
I mean now more and more women have a cancer with breast,which is a big risk for us.
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Barbara Jean on 10/17/2010 23:33:20
The article is good in general. But the 2nd and 3rd paragraph seem to contradict each other.

Is there someone who can explain why the author said that on the one hand, 'Decreased levels of CoQ10 have been found in women with breast cancer....?' From this statement I think the author is saying that the less CoQ10 you have in your system, the more chance there is of being diagnosed with breast cancer.

While on the other hand, in the next paragraph, the author says, '...women with highest concentrations of plasma coenzyme Q10 were more than twice as likely as those who had lowest amounts to be diagnosed with breast cancer.' From this comment I think the author is saying that women are twice as likely to be diagnosed with breast cancer if they have higher concentrations of CoQ10 in their system.

I'm seriously confused about this. I'm hoping someone else might read these comments and have a different take on what's being said and can share that. Because I would love to take this product, as it seems it has lots and lots of positive medicinal properties that my mind and body can certainly use. But certainly not if it increases my chances of getting breast cancer!

I appreciation any opinions or information you can provide. Thank you. Barb
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fake louis vuitton on 11/04/2010 02:08:34
that is it sit
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