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Vitamin D fights lung cancer?

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Sat Aug 24, 2013 (foodconsumer.org) -- Lung cancer is deadly but a recent study in American Journal of Clinical Nutrition suggests that vitamin D may help prevent the disease.

T.Y. Cheng from Fred Hutchinson Cancer Research Center in Seattle, WA and colleagues conducted the study and found non-smokers who had intake of greater than 800 IU of vitamin D per day were almost 63% less likely to be diagnosed with lung cancer, compared with those who had intake of less than 100 IU per day.

The study was based on data from 128,779 postmenopausal women including 1,771 cases of lung cancers in the Women's Health Initiative study. Among the participants, 12% received 1 gram of calcium plus 400 IU of vitamin D3 per day in the Calcium/Vitamin D Trial.  Total vitamin D intake was surveyed at baseline through food-frequency questionnaires.

The study also found that vitamin A intake does not seem to modify the association between vitamin D and risk of lung cancer.  However, in the calcium/vitamin d trial, the preventative effect of vitamin D was found only in women who had intake of vitamin A (retinol) below 1000 ug per day.  

The researchers concluded "Vitamin D intake was associated with a lower lung cancer risk in never-smoking, postmenopausal women. Lower vitamin A intake may be important for a beneficial association of 1 g Ca + 400 IU vitamin D3 supplementation with lung cancer." (david liu)

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