foodconsumer.org: Grape seed extract may help prevent Alzheimer's

Grape seed extract may help prevent Alzheimer's
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admin on 06/30/2008 00:39:00
 
SUNDAY June 29, 2008 (foodconsumer.org) -- A study conducted by J Wang and
colleagues from Mount Sinai School of Medicine in New York suggests that taking
grape seed extract supplements may help prevent or even treat Alzheimer's
disease.
Published on June 18 in the Journal of Neuroscience, the study showed that grape
seed polyphenolic extract significantly inhibits amyloid beta-protein
aggregation into high-molecular-weight oligomers in vitro.
The study also showed that when orally administered to lab mice, the extract
dramatically attenuates the cognitive deterioration commonly experienced by
Alzheimer's patients.
Alzheimer's disease is a neurodegenerative disease characterized by progressive
impairments in memory and cognition.  There is no cure for the disease.
Extracellular accumulation of soluble high-molecular-weight oligomers has been
proposed as being responsible for Alzheimer's dementia and memory deficits in
mice with a disorder similar to human Alzheimer’s disease.
By Ben Wasserman, and edited by Heather Kelley.
Jun 29, 2008 - 10:10:13 AM