foodconsumer.org: Vitamin K2 May Cut Coronary Heart Disease Risk Vitamin K2 May Cut Coronary Heart Disease Risk ================================================================================ admin on 01/23/2010 18:20:00 Saturday Jan 23, 2010 (foodconsumer.org) -- Taking vitamin K2 supplements or eating lots of green vegetables may help cut risk for coronary heart disease, a study in the Sept 2009 issue of Nutrition, Metabolism, and Cardiovascular Diseases suggests. Previous studies have already shown that vitamin K dependent proteins inhibit vascular calcification, a precursor for cardiovascular disease. The study, led by Gast G. C. and colleagues from University Medical Center Utrecht in the Netherlands, was meant to examine the association between the intake of dietary vitamins K1 and K2 and incidence of coronary heart disease. For the study, the researchers followed 16,057 women, aged 49 to 70, for an average of eight years. The participants were surveyed when entering the study for their intake of vitamin K and other nutrients. The average intakes of vitamin K1 and K2 were 211.7 microg/d and 29.1 microg/d, respectively. The women were free of CHD at baseline. During the follow-up, 480 incident cases of CHD were recorded. When other risk factors and dietary factors were considered, an inverse association became apparent between intake of vitamin K2 and incidence of coronary heart disease. Specifically, intake of each 10 microg/d vitamin K2 was associated with a nine percent reduction in coronary heart disease. The researchers found the association was mainly due to vitamin K2 subtype MK-7, MK-7 and MK-9. No similar association was found for vitamin K1. Coronary heart disease, also called coronary artery disease, is a condition in which plaque builds up inside the coronary arteries, leading to atherosclerosis. The plaque consists of fat, cholesterol, calcium and other substances. Vitamin K is found in large quantity in vegetables, including raw parsley, Swiss chard, kale, broccoli, watercress, green leafy lettuce, spinach. Small quantities of vitamin K are also found in soybean oil and canola oil and other plant-based foods. A health observer said this study suggests that eating vegetables may prevent coronary heart disease; conversely, eating insufficient vegetables may increase the risk. Reporting by David Liu and editing by Rachel Stockton