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# Ascorbate against MSG induced neurotoxicity
- URL: https://www.foodconsumer.org/ascorbate_against_msg_induced_neurotoxicity_0524160124/
- Published: 2016-05-24T14:23:00.000Z
- Updated: 2026-09-15T14:38:12.000Z
- Description: Researchers at the University of Navarra reported that glutamate kills dopaminergic neurons by driving oxidative stress, and that vitamin C protected the cells in a laboratory model of human neurons exposed to prolonged glutamate.
- Author: Food Consumer
- Tags: Vitamins, Nutrition, #vivvo-import

You do not have to worry about the neurotoxicity of Monosodium glutamate if you have sufficient intake of vitamin C or ascorbic acid or ascorbate, a new study suggests. Vitamin C is known for many health benefits, but now the study gives food consumers another reason to use vitamin C.Monosodium glutamate or MSG makes foods umami! But scientific evidence has shown that the savory ingredient is a neurotoxin.Researchers at University of Navarra in Pamplona, Spain proposed and demonstrated that glutamate kills dopaminergic neurons by excessively stimulating oxidative stress.The researchers also found vitamin C as a potent antioxidant mediates redox balance and renders neuroprotection against glutamate induced neurotoxicity. (David Liu)Source: *Ballaz S, Morales I, Rodríguez M, Obeso JA. Ascorbate prevents cell death from prolonged exposure to glutamate in an in vitro model of human dopaminergic neurons. J Neurosci Res. 2013 Dec;91(12):1609-17\. doi: 10.1002/jnr.23276\. Epub 2013 Aug 30.*