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# Breast cancer and endometrial cancer, which is more dangerous?
- URL: https://www.foodconsumer.org/breast_cancer_and_endometrial_cancer_1020130248/
- Published: 2013-10-20T03:47:00.000Z
- Updated: 2026-09-22T16:10:00.000Z
- Description: Among 2,027 women in SEER data diagnosed with both breast and endometrial cancer, 63.9 percent developed breast cancer first. The cumulative five-year risk of death after the second diagnosis was nearly four times more likely to come from breast than endometrial cancer.
- Author: Food Consumer
- Tags: Disease, Health News, #vivvo-import

Sunday Oct 20, 2013 (foodconsumer.org) -- Breast cancer seems more dangerous than endometrial cancer. A new study most recently published in Oncology Lettetter finds a woman diagnosed with both breast cancer and endometrial cancers were more likely to die from breast cancer than endometrial cancer. If a woman is destined to develop both cancers, it is likely that she is diagnosed with breast cancer first.

T. M. Martin-Dunlap from Department of Surgery, Washington University in St. Louis, MO, USA and colleagues conducted the study to determine the risk of death or mortality in women diagnosed with breast cancer endometrial cancer. The researchers analyzed SEER data and found that among 2027 women diagnosed with both malignancies 63.9% developed breast cancer first and the rest developed endometrial cancer first.

Regional lymph nodes were more likely to be found in women diagnosed with breast cancer than women diagnosed with endometrial cancer, 25.8% vs. 4.3%.

Women whose disease came with a high tumor grade in the case of endometrial cancer, nodal positivity and estrogen receptor negative (ER-) breast cancer were at higher risk of death (By death, it means the patient can't survive for five years or longer after diagnosis). Estrogen receptor negative breast cancer is harder to treat, compared with estrogen receptor positive (ER+) breast cancer.

Overall, the researchers found 4.1% women died from breast cancer, 3.1% from endometrial cancer and 8.8% from other causes.

The study concluded "for women diagnosed with breast and endometrial cancer, the cumulative risk of mortality at five years following the second cancer diagnosis is nearly four times more likely to be due to breast cancer than endometrial cancer." (DL)