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# Cox-2 inhibitors may help Desmoid tumor
- URL: https://www.foodconsumer.org/cox-2_inhibitors_may_help_desmoid_tumors_1121160233/
- Published: 2016-11-21T15:32:00.000Z
- Updated: 2026-09-22T16:33:38.000Z
- Description: A case report in the World Journal of Surgical Oncology describes a 57-year-old woman whose pancreatic-head desmoid tumor was removed and who then took celecoxib, with complete remission and no recurrence within two years. The authors say more research is needed.
- Author: Food Consumer
- Tags: Drug, Health News, #vivvo-import

[Desmoid tumor](https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&cad=rja&uact=8&sqi=2&ved=0ahUKEwj%5FloKV2rrQAhWH5IMKHYIJDZkQFggeMAE&url=https%3A%2F%2Fghr.nlm.nih.gov%2Fcondition%2Fdesmoid-tumor&usg=AFQjCNHRWcfeKmswf1ZPud7KwRstDeKbiA&sig2=g3cniLfESaLWeQnFvHtQCg&bvm=bv.139250283,d.amc) is noncancerous, but locally aggressive neoplasms with high odds of postoperative recurrence. A report released this year in World Journal of surgical Oncology suggests that Cyclooxygenase-2 (cox-2) inhibitors like [celecoxib ](https://en.wikipedia.org/wiki/Celecoxib?ref=foodconsumer.org#Anti-cancer)may help get this tumor into complete postoperative remission.

The case report involved a 57-year old woman who suffered recurrent epigastric pain and weight loss. She was diagnosed with a 10-cm tumor "over the pancreatic heat region and dilation of the pancreatic duct." After the tumor was surgically removed, she was treated with celecoxib and experienced complete remission. Within two years of the treatment, she did not have local recurrence or distant metastasis.

The long term efficacy of celecoxib in this case remained unknown. Further research is needed to confirm the effect of celecoxib in treating Desmoid tumor.

Cox-2 inhibitors like celecoxib are often used to treat inflammation, pain and fever. Cox-2 inhibitors are commonly used to treat medical conditions including ankylosing spondylitis, familial adenomatous polyposis, fibromatosis, juvenile rheumatoid arthritis, migraine, osteoarthritis, pain, period pain, rheumatoid arthritis and spondyloarthritis. In the U.S., celecoxib is the only available cox-2 inhibitor. (David Liu)

[*Yu-Chieh Wang and Jia-Uei Wong, Complete remission of pancreatic head desmoid tumor treated by COX-2 inhibitor—a case report, World Journal of Surgical Oncology, 2016 14:190*](https://wjso.biomedcentral.com/articles/10.1186/s12957-016-0944-z?ref=foodconsumer.org)