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# Current Animal Food GRAS Notices Inventory
- URL: https://www.foodconsumer.org/current_animal_food_gras_notices_inventory_0731140558/
- Published: 2014-07-31T17:44:00.000Z
- Updated: 2026-09-22T15:47:16.000Z
- Description: An FDA table of animal food GRAS notices current through July 31, 2014, listing each notifier, the substance, its intended use and target species, the filing date and the agency's response letter.
- Author: Food Consumer
- Tags: Food Chemicals, #vivvo-import

Cited directly from FDA website

The following table is provided on an interim basis, until the Animal Food GRAS Notices Inventory database is launched. The data provided are current through 7/31/2014\. A decision on FDA's part to file a submission as a GRAS notice has not reflected our judgment as to whether the notice addressed all issues or discussed all critical data or information.

Persons using assistive technology may not be able to fully access information in the submissions. For assistance, please call 240-276-9300.

| AGRN (select AGRN No. for detailed record)                                                                                                                                  | Notifier                                                                   | Substance                                                                                                                            | Intended Use                                                                                                                                                                                                                                                                        | Intended Species                                                                                                                                                  | Date of Filing | FDA's Letter (select to view letter)                                                                                                                                                                                              |
| --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------- | -------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| [1](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM284079.pdf?ref=foodconsumer.org)(PDF - 387 pages)  | Resonant Biosciences, Inc.                                                 | Chlorine dioxide                                                                                                                     | To be used as a processing aid, with a maximum application rate of 55 ppm per batch, in the production of non-food grade ethanol, food grade ethanol, and distillers grains for animal feed use for food-producing animals.                                                         | Food-producing animals.                                                                                                                                           | 12/21/2010     | [Notice does not provide a basis for a GRAS determination](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM279939.pdf?ref=foodconsumer.org) (PDF - 6 pages)  |
| 2                                                                                                                                                                           | Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology | Penicillin G potassium                                                                                                               | To control the levels of contaminants and their by-products in the production of non-food grade and food grade ethanol and distillers grain for target animal feed use at a level not to exceed 6 ppm of commercial product or 2.7 ppm of penicillin G potassium, in the fermentor. | Livestock including beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses. | 12/23/2010     | [At notifier's request, FDA ceased to evaluate the notice.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM275784.pdf?ref=foodconsumer.org) (PDF - 2 pages) |
| [3](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM284080.pdf?ref=foodconsumer.org)(PDF - 160 pages)  | Hill’s Pet Nutrition Inc.                                                  | alpha-Lipoic acid                                                                                                                    | To be used as an ingredient in dry foods for adult dogs at levels up to 150 ppm (150 mg/kg food or 0.0150%) as a cellular antioxidant and cofactor of enzymes involved in the metabolism of carbohydrates and amino acids.                                                          | Adult dogs (i.e., at least 1 year old).                                                                                                                           | 2/8/2011       | [Notice does not provide a basis for a GRAS determination](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM283953.pdf?ref=foodconsumer.org) (PDF - 5 pages)  |
| 4                                                                                                                                                                           | Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology | Virginiamycin                                                                                                                        | To be used as a processing aid in the production of non-food grade and food grade ethanol at a level not to exceed 6 ppm of commercial product (3 ppm virginiamycin) in the fermentor.                                                                                              | Livestock including beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses. | 3/16/2011      | [At notifier's request, FDA ceased to evaluate the notice.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM275786.pdf?ref=foodconsumer.org) (PDF - 2 pages) |
| [5](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM296194.pdf?ref=foodconsumer.org)(PDF - 67 pages)   | Emerald Carolina Chemicals LLC                                             | Hydrophobic silica                                                                                                                   | As a defoaming component of a defoamer used in the removal of oil from condensed distillers solubles, at levels up to 20 ppm.                                                                                                                                                       | Beef cattle, dairy cattle, poultry (turkey, broiler chickens,and egg laying hens), sheep, goats, and swine.                                                       | 5/12/2011      | [FDA has no questions.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM296144.pdf?ref=foodconsumer.org) (PDF - 3 pages)                                     |
| [6](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM296195.pdf?ref=foodconsumer.org)(PDF - 57 pages)   | Emerald Carolina Chemicals LLC                                             | Polyethylene glycol (400) dioleate                                                                                                   | As an emulsifier component of a defoamer used in the removal of oil from condensed distillers, at levels up to 64 ppm.                                                                                                                                                              | Beef cattle, dairy cattle, poultry (turkey, broiler chickens,and egg laying hens), sheep, goats, and swine.                                                       | 5/12/2011      | [FDA has no questions.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM296145.pdf?ref=foodconsumer.org) (PDF - 3 pages)                                     |
| [7](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM296197.pdf?ref=foodconsumer.org)(PDF - 101 pages)  | Emerald Carolina Chemicals LLC                                             | Polysorbate 60                                                                                                                       | As an emulsifier component of a defoamer used in the removal of oil from condensed distillers solubles, at levels up to 20 ppm.                                                                                                                                                     | Beef cattle, dairy cattle, poultry (turkey, broiler chickens,and egg laying hens), sheep, goats, and swine.                                                       | 5/12/2011      | [FDA has no questions.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM296146.pdf?ref=foodconsumer.org) (PDF - 3 pages)                                     |
| [8](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM300499.pdf?ref=foodconsumer.org)(PDF - 21 pages)   | Rubinum S.A. Animal Health                                                 | *Bacillus cereus*variant toyoi                                                                                                       | To be used as an animal feed ingredient to help maintain the animal's gut microflora.                                                                                                                                                                                               | Livestock including swine, cattle, broiler chickens, turkeys, and rabbits.                                                                                        | 6/10/2011      | [Notice does not provide a basis for a GRAS determination.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM300470.pdf?ref=foodconsumer.org) (PDF - 4 pages) |
| [9](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM304220.pdf?ref=foodconsumer.org)(PDF - 82 pages)   | Vitamin Derivatives, Inc.                                                  | 1-alpha-Hydroxycholecalciferol                                                                                                       | To be used as a dietary source of vitamin D up to 5 micrograms per kilogram in the finished feed.                                                                                                                                                                                   | Broiler chickens.                                                                                                                                                 | 7/13/2011      | [Notice does not provide a basis for a GRAS determination.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM304180.pdf?ref=foodconsumer.org) (PDF - 6 pages) |
| [10](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM312305.pdf?ref=foodconsumer.org)(PDF - 61 pages)  | Gevo                                                                       | Inactivated modified*Saccharomyces cerevisiae*                                                                                       | As a component of animal feed when used in the fermentation and distillation of corn to produce isobutanol.                                                                                                                                                                         | Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, sheep, dogs, cats, rabbits, guinea pigs and horses.                                        | 8/25/2011      | [Notice does not provide a basis for a GRAS determination.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM312303.pdf?ref=foodconsumer.org) (PDF - 4 pages) |
| 11                                                                                                                                                                          | Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology | Penicillin G potassium                                                                                                               | To control the levels of contaminants and their byproducts in the production of food grade and no-food grade ethanol and distillers grain for target animal feed use at a level not to exceed 6 ppm of commercial product, or 3.0 ppm of Penicillin G in the fermentor.             | Livestock including beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses.  | 9/15/2011      | [At notifier's request, FDA ceased to evaluate the notice.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM308795.pdf?ref=foodconsumer.org) (PDF - 2 pages) |
| 12                                                                                                                                                                          | Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology | Virginiamycin                                                                                                                        | To be used as a processing aid in the production of food and non-food grade ethanol at a level not to exceed 6 ppm of commercial product (3 ppm Virginiamycin) in the fermentor.                                                                                                    | Livestock including beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses. | 9/15/2011      | [At notifier's request, FDA ceased to evaluate the notice.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM308796.pdf?ref=foodconsumer.org) (PDF - 2 pages) |
| 13                                                                                                                                                                          | Gevo                                                                       | Isobutanol distillers grain                                                                                                          | To be used as a component of animal feed.                                                                                                                                                                                                                                           | Livestock include: beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine and sheep. Pets include: dogs, cats, rabbits, guinea pigs, and horses.   | 9/29/2011      | [At notifier's request, FDA ceased to evaluate the notice.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM315643.pdf?ref=foodconsumer.org) (PDF - 2 pages) |
| [14](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM352512.pdf?ref=foodconsumer.org)(PDF - 576 pages) | DSM Nutritional Products                                                   | Phytase enzyme produced by an*Aspergillus oryzae*strain expressing a synthetic gene coding for a 6-phytase from*Citrobacter braakii* | To increase the digestibility of phytin-bound phosphorous or to increase phosphorous availability from phytate in poultry diets when fed at the rate of 250-4000 FYT/kg feed.                                                                                                       | Poultry (turkey, broiler chickens, and egg laying hens)                                                                                                           | 11/14/2012     | [FDA has no questions.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM352523.pdf?ref=foodconsumer.org) (PDF - 3 pages)                                     |
| [15](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM402395.pdf?ref=foodconsumer.org)(PDF - 505 pages) | DSM Nutritional Products                                                   | Phytase enzyme produced by an*Aspergillus oryzae*strain expressing a synthetic gene coding for a 6-phytase from*Citrobacter braakii* | To increase the digestibility of phytin-bound phosphorous or to increase phosphorous availability from phytate in swine diets when fed at the rate of 500-4000 FYT/kg feed.                                                                                                         | Swine                                                                                                                                                             | 8/8/2013       | [FDA has no questions.](http://www.fda.gov/downloads/AnimalVeterinary/Products/AnimalFoodFeeds/GenerallyRecognizedasSafeGRASNotifications/UCM402193.pdf?ref=foodconsumer.org) (PDF - 3 pages)                                     |
| 16                                                                                                                                                                          | Metabolic Explorer                                                         | L-methionine 85% produced by a genetically modified*Escherichia coli* K-12                                                           | Nutrient at levels up to 0.3% in animal feed                                                                                                                                                                                                                                        | All animals                                                                                                                                                       | 1/3/2014       | Pending                                                                                                                                                                                                                           |
| 17                                                                                                                                                                          | DSM Nutritional Products                                                   | Canthaxanthin                                                                                                                        | To be used in breeder hen diets at the rate of 6 mg /kg of feed as a nutritive antioxidant to support the development of chicks.                                                                                                                                                    | Breeder hens used for hatching egg production.                                                                                                                    | 7/22/2014      | Pending                                                                                                                                                                                                                           |

Page Last Updated: 07/31/2014