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# Decaffeinated green coffee bean extract for weight loss
- URL: https://www.foodconsumer.org/decaffeinated_green_coffee_bean_extract_for_weight_loss_05281408/
- Published: 2014-05-28T09:58:00.000Z
- Updated: 2026-09-22T16:01:50.000Z
- Description: Mice on a high-fat diet supplemented with 0.3% decaffeinated green coffee bean extract for 11 weeks did not gain weight, and 0.9% was no more potent. The authors put 0.3% at about 1,460 mg a day for a 60-kg person — ten times the chlorogenic acid of dark roasted coffee.
- Author: Food Consumer
- Tags: Obesity, Avoiding Illness, #vivvo-import

Wednesday may 28, 2014 (foodconsumer.org) -- A new study in Evidence-Based Complementary and Alternative Medicine suggests taking decaffeinated green coffee bean extract pills for weeks can significantly prevent weight gain or obesity or result in weight loss depending upon an individual dietary habit.

The study led by Su Jin Song at Yonsei University in Seoul, Republic of Korea and colleagues shows that mice eating a high fat diet supplemented with 0.3% decaffeinated green coffee bean extract for 11 weeks prevented weight gain.

Previous studies have shown that supplementation of decaffeinated green coffee bean extract in a dose of 400 mg per day for 60 days induced weight loss in overweight individuals. One of chlorogenic acids known as 5-caffeoylquinic acid has also been found mainly responsible for the anti-obesity effect of green coffee bean extract in mice.

In addition to its anti-obesity properties, decaffeinated green coffee bean extract delivered in drinking water improved high fat diet induced insulin resistance in mice as shown in early studies.

The current study was intended to test decaffeinated green coffee bean extract, which was free of caffeine in mice for its anti-obesity effect, in mice fed on a high fat diet which would otherwise induce obesity and insulin resistance.

The doses of decaffeinated green coffee bean extract used in the study was 0.1%, 0.3% and 0.9% per kg of diet. The researchers found 0.3% is the minimum dose that was needed to provide an anti-obesity effect and 0.9% did not show a higher potency than 0.3%. The dose is equivalent to 1,460 mg extract/60 kg body weight per day in a person with 60 kg body weight. 

To have an equivalent amount of chlorogenic acid, 10 times more dark roasted coffee is needed. Raw green coffee bean extract contains much higher amounts of chlorogenic acid that is needed for its anti-obesity activity.

The current study shows that 0.3% decaffeinated green coffee bean extract (which contain 0.05% 5-caffeoylquinic acid) reduced a maximum of 31% reduction in weight gain in mice fed on a high fat diet.

Decaffeinated green coffee bean extract attenuated high-fat-diet-induced adipogenesis by modulating the expression of genes involved in WNT10b- and galanin-mediated adipogenesis in the epididymal adipose tissue.

Decaffeinated green coffee bean extract was also found in the study to attenuate inflammation and insulin resistance induced by a high fat diet. This means that decaffeinated green coffee bean extract may also prevent type 2 diabetes mellitus.

The study also shows that decaffeinated green coffee bean extract contains ingredients other than 5-caffeoylquinic acid that also contribute to its anti-obesity property.

Green coffee bean extract side effects have not been reported.

Coffee drinking has been associated with health benefits such as reduced risk of Parkinson’s disease, Alzheimer’s disease, and certain types of cancer, but heavy coffee drinking may increase risk of sleep disorders, hypokalemia, and cardiac arrhythmias. Recent studies have shown that coffee prevents obesity, metabolic disorders particularly type 2 diabetes mellitus.

Green coffee bean extract pills can be purchased on the internet or local health stores. For those who do not want to ingest caffeine, they may check and see if decaffeinated green coffee bean extract is available. (David Liu, PHD)