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# Dietary folate lowers gastric cancer
- URL: https://www.foodconsumer.org/dietary_folate_lowers_gastric_cancer_0822160944/
- Published: 2016-08-22T10:44:00.000Z
- Updated: 2026-09-22T16:13:35.000Z
- Description: A South Korean case-control study in Cancer Research found people with high dietary folate intake were 30 percent less likely to be diagnosed with gastric cancer than those with low intake, with the protection strongest among carriers of certain gene variants.
- Author: Food Consumer
- Tags: Vitamins, Nutrition, #vivvo-import

Monday Aug 22, 2016 (foodconsumer.org) -- Dietary folate is important for pregnant women as folate deficiency in pregnant women is linked to high risk of birth defects. A new study conducted in South Korea now suggests sufficient intake of folate may also help reduce risk of gastric cancer or stomach cancer. 

The case-control study published in Cancer Research shows those who had high intake of dietary folate were 30% less likely to be diagnosed with gastric cancer than those who had low intake. 

The study also finds low intake of dietary folate was linked to a significantly higher risk for gastric cancer among people with certain single nucleotide polymorphisms (SNPs). With high intake of folate, the genetic makeup did not have a big impact on the risk. This means that the protective effect of folate against gastric cancer is particularly significant among people with certain genetic profiles. 

Foods high in folate include asparagus, spinach, turnip greens, romaine lettuce, bok choy, parsley, and broccoli. Many processed foods and flours are fortified with synthetic folate. But consumption of artificial folate has been linked to increased risk for breast cancer. 

In addition to folate, some studies have indicated salty foods can be a major risk factor for stomach cancer for people with bacteria called Helicobacter pylori. It is now known that high salt can prompt the bacteria to produce a carcinogen that causes damage to the stomach. Late dinner or night-snacking can also increase the risk of gastric cancer. (David Liu)

[*Jeongseon Kim, Woori Kim, Hae Dong Woo, Jeonghee Lee, Il Ju Choi, Young Woo Kim, Joohon Sung. Dietary folate, one-carbon metabolism-related genes, and gastric cancer risk in Korea. \[abstract\]. In: Proceedings of the Fourth AACR International Conference on Frontiers in Basic Cancer Research; 2015 Oct 23-26; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2016;76(3 Suppl):Abstract nr A10.*](http://cancerres.aacrjournals.org/content/76/3%5FSupplement/A10.short?ref=foodconsumer.org)