> ## Content Index
> Fetch the complete content index at: https://www.foodconsumer.org/llms.txt
> Use this file to discover other available public pages before exploring further.

# Dietary supplements and Alzheimer’s disease
- URL: https://www.foodconsumer.org/dietary_supplements_and_alzheimer_s_disease_0921130623/
- Published: 2013-09-21T19:22:00.000Z
- Updated: 2026-09-22T16:01:46.000Z
- Description: A roundup of research citations on Alzheimer's disease: high serum homocysteine, head trauma, alcohol and tobacco appear on the risk side, while vitamin E and C, B vitamins, resveratrol, omega-3 fats and melatonin may help prevent or ease symptoms, though the studies disagree.
- Author: Food Consumer
- Tags: Supplements, Nutrition, #vivvo-import

Some interesting research reports are cited below. It seems that high serum homocysteine, head trauma and alcohol and tobacco are linked to high risk of Alzheimer’s disease while dietary supplements antioxidants such as vitamin E and C, resveratrol, B vitamins and omega 3 fatty acids such as DHA found in oily fish and melatonin may help prevent or relieve symptoms of Alzheimer’s disease although not all studies are consistent. Specifically, carnitine, choline, curcumin, folic acid, fruits and vegetables, thiamin, vitamin B6, vitamin B12 and vitamin E among others may help prevent Alzheimer's disease, according to Linus Pauling Institute. Also anything such as high iron in meat that promotes oxidation or increases oxidative stress can increase the risk of Alzheimer's disease.

[Plasma homocysteine as a risk factor for dementia and**Alzheimer's disease**](http://www.nejm.org/doi/full/10.1056/nejmoa011613?ref=foodconsumer.org)

S Seshadri, A Beiser, J Selhub… - … England Journal of …, 2002 - Mass Medical Soc

[Early vitamin E **supplementation** in young but not aged mice reduces Aβ levels and amyloid deposition in a transgenic model of **Alzheimer's disease**](http://www.fasebj.org/content/18/2/323.short?ref=foodconsumer.org)

S Sung, Y Yao, K Uryu, H Yang, VMY LEE… - The FASEB Journal, 2004 - FASEB

[Head trauma as a risk factor for **Alzheimer's disease**: a collaborative re-analysis of case-control studies](http://ije.oxfordjournals.org/content/20/Supplement%5F2/S28.short?ref=foodconsumer.org)

JA Mortimer, CM Van Duijn, V Chandra… - International journal of …, 1991 - IEA

[Vitamin E and vitamin C **supplement** use and risk of incident **Alzheimer disease**](http://journals.lww.com/alzheimerjournal/Abstract/1998/09000/Vitamin%5FE%5Fand%5FVitamin%5FC%5FSupplement%5FUse%5Fand%5FRisk%5Fof.1.aspx?ref=foodconsumer.org)

MC Morris, LA Beckett, PA Scherr… - **Alzheimer Disease** & …, 1998 - journals.lww.com

[Dietary **supplementation** with resveratrol reduces plaque pathology in a transgenic model of **Alzheimer's disease**](http://www.sciencedirect.com/science/article/pii/S0197018608001708?ref=foodconsumer.org)

SS Karuppagounder, JT Pinto, H Xu, HL Chen… - Neurochemistry …, 2009 - Elsevier

[Dietary factors and **Alzheimer's disease**](http://www.sciencedirect.com/science/article/pii/S1474442204008786?ref=foodconsumer.org)

JA Luchsinger, R Mayeux - The Lancet Neurology, 2004 - Elsevier

[Influence of vitamin E and C **supplementation** on lipoprotein oxidation in patients with**Alzheimer's disease**](http://www.sciencedirect.com/science/article/pii/S0891584901005950?ref=foodconsumer.org)

A Kontush, U Mann, S Arlt, A Ujeyl, C Lührs… - Free Radical Biology …, 2001 - Elsevier

[Reduced risk of **Alzheimer disease** in users of antioxidant vitamin**supplements**: the Cache County Study](http://archneur.ama-assn.org/cgi/reprint/61/1/82.pdf?ref=foodconsumer.org)

PP Zandi, JC Anthony, AS Khachaturian… - Archives of …, 2004 - Am Med Assoc

[High-dose B vitamin **supplementation** and cognitive decline in**Alzheimer disease**](http://jama.ama-assn.org/content/300/15/1774.short?ref=foodconsumer.org)

PS Aisen, LS Schneider, M Sano… - JAMA: the journal of …, 2008 - Am Med Assoc

[Early melatonin **supplementation** alleviates oxidative stress in a transgenic mouse model of**Alzheimer's disease**](http://www.sciencedirect.com/science/article/pii/S0891584905004600?ref=foodconsumer.org)

Z Feng, C Qin, Y Chang, J Zhang - Free Radical Biology and Medicine, 2006 - Elsevier

[Alcohol and tobacco consumption as risk factors for **Alzheimer's disease**: a collaborative re-analysis of case-control studies](http://ije.oxfordjournals.org/content/20/Supplement%5F2/S48.short?ref=foodconsumer.org)

AB Graves, CM Van Duijn, V Chandra, L Fratiglioni… - International Journal of …, 1991 - IEA

[Omega?3 **supplementation** in mild to moderate **Alzheimer's disease**: effects on neuropsychiatric symptoms](http://onlinelibrary.wiley.com/doi/10.1002/gps.1857/full?ref=foodconsumer.org)

Y Freund?Levi, H Basun, T Cederholm… - … journal of geriatric …, 2008 - Wiley Online Library

[Docosahexaenoic acid **supplementation** and cognitive decline in**Alzheimer disease**](http://jama.ama-assn.org/content/304/17/1903.short?ref=foodconsumer.org)

JF Quinn, [R Raman](http://scholar.google.com/citations?user=9bh0XNIAAAAJ&hl=en&oi=sra&ref=foodconsumer.org), RG Thomas… - JAMA: the journal of …, 2010 - Am Med Assoc