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# Fish oil supplements preserve brain volume, cognitive function
- URL: https://www.foodconsumer.org/fish_oil_supplements_brain_volume_cognitive_function_0624141020/
- Published: 2014-06-24T11:19:00.000Z
- Updated: 2026-09-22T16:16:04.000Z
- Description: Among 819 people given repeat cognitive tests and brain imaging, fish oil supplement use was associated with less cognitive decline and less brain atrophy in those with normal cognition. The favorable associations appeared only in participants who were APOE e4-negative.
- Author: Food Consumer
- Tags: Supplements, Nutrition, #vivvo-import

Tuesday June 24, 2014 (foodconsumer.org) -- As a normal aging process, human's brain volume is getting smaller and smaller, and cognitive function is on the decline. A new study suggests that taking fish oil supplements may help preserve brain volume and cognitive function.

The study was based on data from 229 cognitively normal men and women, 397 patients with mild cognitive impairment and 193 patients with diagnosed Alzheimer's disease. For the study, neuropsychological tests and brain imaging were conducted every 6 months to assess global cognitive function, and cerebral cortex gray matter and hippocampus and ventricular volumes.

As a result, fish oil supplementation was found associated with significantly lower mean cognitive decline on the Alzheimer's Disease Assessment Scale and higher Mini-Mental State Examination scores among participants with normal cognitive function.

The associations between use of fish oil supplements and favorable outcomes were observed on in participants who were APOE ε4-negative.

The study also found use of fish oil supplements was also correlated with less atrophy in one or more brain regions in the brain.

The study was conducted by scientists at Warren Alpert Medical School of Brown University in Providence, RI, USA. (david Liu, PHD)

Daiello LA, Gongvatana A, Dunsiger S, Cohen RA, Ott BR; Alzheimer's Disease Neuroimaging Initiative. Association of fish oil supplement use with preservation of brain volume and cognitive function. Alzheimers Dement. 2014 Jun 18\. pii: S1552-5260(14)00079-X. doi: 10.1016/j.jalz.2014.02.005.