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# More evidence suggests fructose boosts heart disease risk
- URL: https://www.foodconsumer.org/fructose_boosts_heart_disease_risk_0729110800/
- Published: 2011-07-28T08:59:00.000Z
- Updated: 2026-09-22T15:44:04.000Z
- Description: Adults who took 25 percent of their calories from fructose or high fructose corn syrup for just two weeks showed higher LDL cholesterol, triglycerides and apolipoprotein-B. Glucose produced no such change. US dietary guidelines allow added sugar up to that same 25 percent.
- Author: Food Consumer
- Tags: Food, Nutrition, Fructose, Heart Disease, #vivvo-import

By David Liu, Ph.D. 

Thursday July 29, 2011 (foodconsumer.org) -- Eating the amount of sugar recommended by the U.S. Dietary Guidelines increases the risk of heart disease, according to a study scheduled to be released in the Journal of Clinical Endocrinology & Metabolism.

The study found adult men and women who ate a diet with 25 percent of calories from high fructose corn syrup for merely two weeks had increased plasma cholesterol and triglycerides, which are already associated with increased risk for heart disease.

The Endocrine Society - the publisher of the journal says in a statement that "The American Heart Association recommends that people consume only five percent of calories as added sugar." And a health observer suggests that intake of added sugar should be zero to minimize the risk from this food.

The Dietary Guidelines for Americans 2010 recommends no more than 25 percent of added sugar should be used in a person's diet.

The study was intended to examine how fructose, high fructose corn syrup and glucose would affect young overweight and normal weight adults when these sugars are used as 25 percent of the total calories as recommended as the upper limit in the dietary guidelines.

Kimber Stanhope, Ph. D., of the University of California, Davis and colleagues found when subjects used a diet with 25 percent of calories from fructose or high fructose corn syrup for two weeks, they were facing an elevated risk for cardiovascular disease.

The association was not found with glucose consumption, the authors said.

To be exact, the researchers found subjects eating a diet with 25 percent of total calories from fructose or high fructose corn syrup increased the levels of LDL cholesterol, triglycerides and apolipoprotein-B in their blood within two weeks.

Apolipoprotein-b is known to lead to formation of plaques that cause vascular disease, according to the journal publisher's statement.

"These results suggest that consumption of sugar may promote heart disease," said Stanhope. 

"Additionally our findings provide evidence that the upper limit of 25 percent of daily calories consumed as added sugar as suggested by The Dietary Guidelines for American 2010 may need to be re-evaluated."

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