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# Fructose linked to increased fat synthesis - study
- URL: https://www.foodconsumer.org/fructose_linked_to_increased_fat_synthesis_0418141105/
- Published: 2014-04-18T12:05:00.000Z
- Updated: 2026-09-22T16:21:33.000Z
- Description: In a study from University Hospital Zurich, men consuming 40 or 80 grams of fructose a day raised serum palmitate about 20%, while the same dose of sucrose or glucose did not. High doses of both fructose and sucrose raised fasting long-chain acylcarnitines.
- Author: Food Consumer
- Tags: Food, Nutrition, #vivvo-import

A new study published 2014 in The Journal of Clinical Endocrinology & Metabolism suggests that eating a lot of high fructose corn syrup may increase the risk of developing obesity.

The study led by Michel Hochuli and colleagues from University Hospital Zurich in Zurich, Switzerland shows that men having moderate (40 grams per day) or high (80 grams per day) intake of fructose increased by about 20% the concentration of serum palmitate, a type of fatty acid, compared with high (80 grams per day) intake of sucrose and glucose or with baseline.

On the other hand, high intake of sucrose or glucose (80 grams per day) did not increase the production of palmitate. However, both sucrose and fructose in the high dose (80 grams per day) increased fasting long-chain acylcarnitines.

The study concluded "When consumed in moderate amounts, fructose but not sucrose or glucose in SSB increases fatty acid synthesis (palmitate), whereas fasting long-chain acylcarnitines are increased after both fructose and sucrose, indicating an impaired β-oxidation flux."

Fructose is found high in beverages and processed foods with added high fructose corn syrup. (David Liu)