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# Hesperidin plus calcium supplement prevents bone loss in postmenopausal women
- URL: https://www.foodconsumer.org/hesperidin_plus_calcium_bone_loss_0204161134/
- Published: 2016-02-04T12:33:00.000Z
- Updated: 2026-09-15T14:36:53.000Z
- Description: In a small trial of 12 healthy postmenopausal women, a supplement combining calcium and hesperidin improved bone calcium retention by 5.5%, Purdue's Connie Weaver and colleagues report in JCEM. Hesperidin alone did not prevent bone loss in the subjects.
- Author: Food Consumer
- Tags: Supplements, Nutrition, #vivvo-import

Thursday Feb 4, 2016 (foodconsumer.org) -- Dr. Connie Weaver at Purdue University and colleagues have recently reported in JCEM that taking a supplement with both calcium and hesperidin, a flavanone found in citrus fruits, helps prevent bone loss in postmenopausal women.The researchers conducted a small trial of 12 healthy postmenopausal women and found a supplement with calcium and hesperidin helped improve bone calcium retention by 5.5%. Hesperidin alone did not render the preventative effect on bone loss in the subjects.Early animal studies indicated that hesperidin helps prevent bone loss in ovariectomized rats. (David Liu)*Berdine R. Martin, George P. McCabe, Linda McCabe, George S. Jackson, Marie Noelle Horcajada, Elizabeth Offord-Cavin, Munro Peacock, and Connie M. Weaver, Effect of Hesperidin with and without a Calcium (Calcilock®) Supplement on Bone Health in Postmenopausal Women, The Journal of Clinical Endocrinology & metabolism, First Published Online: January 11, 2016*