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# L-carnitine, L-arginine and niacin help erectile dysfunction
- URL: https://www.foodconsumer.org/l-carnitine_l-arginine_and_niacin_erectile_dysfunction_052616011/
- Published: 2016-05-26T14:13:00.000Z
- Updated: 2026-09-15T14:38:23.000Z
- Description: In a 2012 trial of a supplement combining propionyl-L-carnitine, L-arginine and niacin, men with erectile dysfunction saw a small but significant improvement after three months. Up to 40% had better erections and 77% partially responded, the authors report.
- Author: Food Consumer
- Tags: Supplements, Nutrition, #vivvo-import

In a study released in 2012, a nutritional supplement made of propionyl-L-carnitine, L-arginine and niacin was tested for its potential effects on erectile dysfunction. The results show that men with erectile dysfunction experienced a small yet significant improvement in erectile function after 3-month supplementation with this nutraceutical. Up to 40% of patients improved erection while 77% of patients partially responded to the treatment. The authors suggest that this nutritional supplement may be used as first-line or adjunctive treatment to PDE5 inhibitors to treat erectile dysfunction. (David Liu)*Gianfrilli D1, Lauretta R, Di Dato C, Graziadio C, Pozza C, De Larichaudy J, Giannetta E, Isidori AM, Lenzi A. Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a nutraceutical approach to erectile dysfunction. Andrologia. 2012 May;44 Suppl 1:600-4\. doi: 10.1111/j.1439-0272.2011.01234.x. Epub 2011 Oct 4.*