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# Nocturia may be  sign for future coronary heart disease
- URL: https://www.foodconsumer.org/nocturia_coronary_heart_disease_0708121250/
- Published: 2012-07-08T13:44:00.000Z
- Updated: 2026-09-22T16:09:08.000Z
- Description: Following 2,447 men for about 17 years, Mayo Clinic researchers found those under 60 who woke to urinate more than twice a night were 68 percent more likely to develop coronary heart disease, though adjustment cut that to a non-significant 36 percent.
- Author: Food Consumer
- Tags: Disease, Health News, #vivvo-import

By David Liu PHD

Sunday July 8, 2012 (foodconsumer.org) -- A new study recently published in BJUI suggests that moderate nocturia may increase risk of coronary heart disease in younger men and death risk in older men.

In the study of 2447 men who were followed for an average of 17 years, moderate nocturia was defined as waking to urinate more than twice per night. Younger men were defined as being younger than 60 years old.

The study led by Deborah J. Lightner of Mayo Clinic, Rochester, MN and colleagues showed younger men with moderate nocturia were 68 percent more likely to develop coronary heart disease later in life than those without nocturia. The increase was attenuated to 36 percent after adjustment for age, body mass index, and urological medications. Researchers said the increase was not significant.

Additionally researchers found Older men with moderate nocturia was 48 percent more likely to die than those without moderate nocturia, even after adjusting for age, BMI, urological medicals and coronary heart disease.

Nevertheless, moderate nocturia was not significantly correlated with the later development of diabetes mellitus or hypertension.

It was concluded that "nocturia may be a marker for increased risk of CHD in younger men, and death in older men."

Coronary heart disease also known as coronary artery disease is a major form of heart disease. This disease can be reversed by following a plant-food based diet, according to Dr. T Colin Campbell, a Cornell University nutrition professor.