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# Polyunsaturated fat linked to epithelial ovarian cancer
- URL: https://www.foodconsumer.org/polyunsaturated_fat_linked_to_epithelial_ovarian_cancer_09051412/
- Published: 2014-09-05T13:43:00.000Z
- Updated: 2026-09-22T16:10:25.000Z
- Description: People eating the most polyunsaturated fat were 22% more likely to develop epithelial ovarian cancer than those eating the least. No link appeared for total, animal, plant, saturated or monounsaturated fat, cholesterol or fatty fish. The author points to omega-6 from vegetable oils.
- Author: Food Consumer
- Tags: Food, Nutrition, #vivvo-import

Friday Sept 5, 2014 (foodconsumer.org) -- A new study suggests that eating too much polyunsaturated fat may increase the risk o epithelial ovarian cancer. Because much of the dietary polyunsaturated fat is omega-6 fat that largely comes from vegetable oils like safflower oil, corn oil and soybean oil, this study suggests that eating omega-6 fatty acids can increase this type of malignancy. 

Omega-6 fatty acids have been found in previous studies to increase risk of obesity and cardiovascular disease because of its inflammatory effects. The current study found those who ate large amounts of polyunsaturated fat were 22% more likely to develop epithelial ovarian cancer than those who ate low amounts of this fat.

The study found no association between invasive epithelial ovarian cancer and consumption of total fat, animal/plant fat, saturated fat, cholesterol, monounsaturated fat, or fatty fish like salmon.

A growing body of evidence suggests that eating large amounts of omega-6 fatty acids can induce adverse effects and increase risk of a number of chronic diseases in addition to ovarian cancer. One should limit their intake of omega-6 polyunsaturated fat and increase intake of omega 3 fatty acids. Omega 3 fatty acids can offset the adverse effects of omega 6 fatty acids. (david Liu, PHD)

Merritt MA, Riboli E, Weiderpass E, Tsilidis KK, Overvad K, Tjønneland , Hansen L, Dossus L, Fagherazzi G, Baglietto L, Fortner RT, Ose J, Steffen A, Boeing H, Trichopoulou A, Trichopoulos D, Lagiou P, Masala G, Sieri S, Mattiello A, Tumino R, Sacerdote C, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Hjartåker A, Gram IT, Quirós JR, Obón-Santacana M, Molina-Montes E, Huerta Castaño JM, Ardanaz E, Chamosa S, Sonestedt E, Idahl A, Lundin E, Khaw KT, Wareham N, Travis RC, Rinaldi S, Romieu I, Chajes V, Gunter MJ. Dietary fat intake and risk of epithelial ovarian cancer in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol. 2014 Aug 21\. pii: S1877-7821(14)00137-4.