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# Raspberry ketone based supplement helps weight loss
- URL: https://www.foodconsumer.org/raspberry_ketone_weight_loss_1229131129/
- Published: 2013-12-29T12:28:00.000Z
- Updated: 2026-09-22T16:15:56.000Z
- Description: Of 45 obese adults who completed a diet-and-exercise trial, those also taking METABO - a supplement combining raspberry ketone, caffeine, capsaicin, garlic, ginger and Citrus aurantium - lost more fat mass and waist girth and reported more energy. No adverse events were observed.
- Author: Food Consumer
- Tags: Supplements, Nutrition, #vivvo-import

Sunday Dec. 29, 2013 (foodconsumer.org) -- A study in BioMedcentral suggests that taking a weight loss dietary supplement called METABO is effective in helping weight loss in obese men and women. METABO is a supplement consisting of multiple nutritional ingredients including raspberry ketone, caffeine, capsaicin, garlic, ginger and Citrus aurantium (Prograde Metabolism™ \[METABO\]).

The study led by Hector L Lopez from The Center for Applied Health Sciences in Stow, OH and colleagues shows that obese participants who took the raspberry ketone based METABO supplement for weight weeks while participating in a weight loss program lost more weight than those who participated in the weight loss program only.

Following the weight loss program, 70 obese participants followed a calorie restricted diet and engaged in exercise training. Half also received the weight loss METABO supplement daily for weight weeks.

Of the 45 obese individuals who completed the trial, those who used the raspberry ketone based supplement lost significantly more fat mass, lean mass, waist girth, and increased energy levels.

In the first 4 weeks of supplementation, elevated serum leptin and decreased serum resistin was observed in those who took the dietary supplement, compared with those who did not take the supplement. 

Leptin inhibits appetite and individuals with high levels of leptin tend to eat less. In most cases, people can't follow a calorie-restricted diet, which is necessary for weight loss. Now raspberry ketone can lead to a high level of leptin, which is why participants taking the supplement lost more weight. High levels of resistin were found in obese people. Decreased levels of resistin are desired. 

No adverse events were observed in those taking the raspberry ketone based supplement.

The researchers concluded "METABO administration is a safe and effective adjunct to an eight-week diet and exercise weight loss program by augmenting improvements in body composition, waist and hip girth. Adherence to the eight-week weight loss program also led to beneficial changes in body fat in placebo."

Raspberry ketones are commonly used by obese people as a weight loss supplement. (DAvid Liu)