> ## Content Index
> Fetch the complete content index at: https://www.foodconsumer.org/llms.txt
> Use this file to discover other available public pages before exploring further.

# Low vitamin D linked to high risk of Alzheimer's disease
- URL: https://www.foodconsumer.org/vitamin_d_alzheimer_s_disease_1013131150/
- Published: 2013-10-13T12:49:00.000Z
- Updated: 2026-09-22T16:13:03.000Z
- Description: In a Danish cohort of 10,186 people followed up to 30 years, those with plasma vitamin D below 25 nmol/L were 25 percent more likely to develop Alzheimer's disease than those above 50 nmol/L, and those below 50 nmol/L were 22 percent more likely to develop vascular dementia.
- Author: Food Consumer
- Tags: Vitamins, Nutrition, #vivvo-import

Sunday Oct 13, 2013 (foodconsumer.org) -- A new study released in the July 18, 2013 issue of Alzheimer's Disease and Dementia has associated low vitamin D in the blood with high risk of Alzheimer's disease and vascular dementia.

S. Afzal from The Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital in Herlev, Denmark and colleagues conducted the study and found people with low vitamin D in their blood were about 20 to 25% increased risk for Alzheimer's disease and vascular dementia.

The researchers noted that vitamin D deficiency has been implicated as a risk factor for Alzheimer's disease and other forms of dementia in some cross-sectional studies.

The current study was intended to establish an association between reduced serum 25-hydroxvitamin D and an increased risk for Alzheimer's disease and vascular dementia in the general population.

Enrolled in the study were 10,186 while men and women in the Danish general population. During a 30-yer follow-up, 418 enrollees developed Alzheimer's disease and 92 developed vascular dementia.

Those whose serum vitamin D was lower than 25 nmol/L, compared with those with greater than 50 nmol/L were 25 % more likely to develop Alzheimer's disease. Or those who in the less than 25th seasonally adjusted vitamin D percenttile, compared with those in the higher than 50th seasonally adjusted vitamin D percentile, were 29% more likely to develop the brain disorder. 

Similarly, 22% higher risk for vascular dementia was found among those with lower than 50 nmol/L, compared with greater than 50 nmol/L, to develop vascular dementia.

The researchers concluded "We observed an association of reduced plasma 25(OH)D with increased risk of the combined end point of AD and vascular dementia in this prospective cohort study of the general population." (JD)