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# Vitamin D deficiency linked to Alzheimer's disease
- URL: https://www.foodconsumer.org/vitamin_d_deficiency_alzheimer_s_disease_0420130918/
- Published: 2013-04-20T10:17:00.000Z
- Updated: 2026-09-22T16:01:41.000Z
- Description: A meta-analysis of 10 observational studies found serum 25OHD concentrations 1.4 standard deviations lower in Alzheimer's patients than in matched healthy controls. The authors treat vitamin D as a possible biomarker of the disease rather than a proven cause.
- Author: Food Consumer
- Tags: Vitamins, Nutrition, Vitamin D, Alzheimer's, #vivvo-import

By Jimmy Downs

Sunday April 20, 2013 (foodconsumer.org) -- A study recently published in the Journal of Alzheimer's disease suggests that vitamin D deficiency or insufficiency can be a risk factor for the disease or at least a biomarker for the disease.

Cedric Annweiler from University of Angers, UNAM in Angers, France and colleagues conducted a meta-analysis of data from a number of previous studies and found "serum 25OHD concentrations were 1.4 standard deviation units lower in AD (Alzheimer's disease) cases compared to cognitively healthy controls."

Vitamin D deficiency has been studied for its association with cognitive function in older adults. The current study was intended to establish an association between hypovitaminosis D (Vitamin D deficiency or insufficiency) and Alzheimer's disease (AD). 

The researchers found 284 relevant studies of which 10 observational studies including 9 case-control studies and one cohort study met the selection criteria for the meta-analysis.

The analysis revealed that Alzheimer's disease "cases had lower serum vitamin D concentrations than matched controls," and the researchers concluded "This reinforces the conceptualization of vitamin D as a ‘neurosteroid hormone’ and as a potential biomarker of AD."

The medical circle says there is no cure for Alzheimer's disease which can eventually completely disable patients leading to death. An estimated 5 million Americans suffer the disease.

However, studies suggest that alternative remedies can help prevent or treat Alzheimer's disease including Shilajit, betaine, green tea, resveratrol, silicon rich mineral water, Mediterranean diet, drinking coffee, curry spice turmeric, red grape juice, ginkgo biloba extract, vitamin C, curcumin, antioxidants, coconut oil cinnamon, vitamin E, grape seed extract, omega-3 fatty acids, dietary polyphenols, and fruit, vegetable juices among others.