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# Vitamin E succinate helps fight pancreatic cancer
- URL: https://www.foodconsumer.org/vitamin_e_succinate_helps_fight_pancreatic_cancer_0427120737/
- Published: 2012-04-27T20:35:00.000Z
- Updated: 2026-09-22T16:09:02.000Z
- Description: In laboratory work reported in Genes and Nutrition, vitamin E succinate curbed proliferation of pancreatic cancer cells, induced apoptosis, and suppressed survivin, a protein that keeps cancer cells from dying.
- Author: Food Consumer
- Tags: Supplements, Nutrition, #vivvo-import

By David Liu, PHD

Friday April 27, 2012 (foodconsumer.org) -- Taking vitamin E succinate supplements may help fight pancreatic cancer, according to a new study in the journal Genes and Nutrition.

The study led by Dorrelyn Patacsil and colleagues from University of the District of Columbia in Washington DC shows that vtamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells.

Survivin is a member of the inhibitor of apoptosis (IAP) family with which cells like cancer cells won't die.

Pancreatic cancer is the fourth leading cancer-related death cause in the United States. The vurvial rate is no more than 5 percent, according to the National Cancer Institute.

Vitamin E succinate is an anlog of the fat-soluble vitamin alpha-cotopherol, which is a common antioxidant.

The current study was to test how Vitamin E succinate affect pancreatic cancer cells. The study shows that this vitamin inhibits cell proliferation and induces apoptosis proteins in pancreatic cancer cells.

Additionally, vitamin E succinate was found to inhibit the expression of survivin and regulate X-linked inhibitor of apoptosis proteins. Apoptosis is a process called programmed cell death which is missing in cancer cells leading to the cancer growth.

Keywords Vitamin E – Vitamin E succinate – Survivin – Pancreatic cancer – Apoptosis