Vitamin D fights pancreatic cancer
By David Liu
A new study published in the July 21 2009 issue of World Journal of Gastroenterology says that the most active form of vitamin D may be used to treat pancreatic cancer.
Chian KC and Chen TC, authors of the study, from the Chang Gung University in Tainwan, China reported that a recent trial had demonstrated that a vitamin D analog known as 19-nor-1alpha,25(OH)(2)D(2) effectively inhibits pancreatic tumor growth in vitro and in vivo via up-regulation of p21 and p27 tumor suppressor genes.
Probably hundreds of even thousands of vitamin D analogs have been synthesized, which can help fight cancer, but lead to less side effects than the most active form of vitamin D called 1alpha,25-dihydroxyvitamin D(3).
Vitamin D has been known to prevent 17 types of malignancies, according to Dr. John Cannell at vitaminDcouncil.org.
High doses of vitamin D are needed to achieve a therapeutic effect against cancers. But high doses of this vitamin may also cause serious symptoms such as hypercalcernia and hypercalciuria.
It is generally believed that up to 10,000 International Units of vitamin D per day is safe. 20-minute sun exposure in the summer can result in 10,000 IU vitamin D. For those who cannot get that much exposure, 5,000 IU of 25-hydroxyvitamin D per day may be taken.
Dr. Cannell says a high serum level of vitamin D ranging from 50–80 ng/mL (or 125–200 nM/L) is needed to help prevent all sorts of cancer.
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offer $40 postal 25(OH)D testing as part of a 5yr trial. You can just opt for a single test or 2 tests each year, or for as long as you want.
It only takes a few minutes to fill out the trial survey (they are trying to link Vitamin D status with hospital treatments) The test is easy to perform, they send you a spring loaded lancet that jabs your finger and you put 2 big drops of blood on the sample sheet, return it in the post and a few days later they send a link to the results.
It's the easiest way to be sure the amount of vitamin D3 you are taking is effective in raising your status into the levels that give your body a store of vitamin d to provide the power to fight cancer and keep it under control.
Dr Davis of the Heartscanblog working in Wisconsin Latitude 42 finds 5000~6000iu/daily is required to keep most of his heart patients around the 60ng mark. But it does vary, hence the need for regular testing until you have determined how much your body requires daily to get into the safer zone.
I know it sounds a lot but 5 minutes full body sun exposure raises over 1000iu so it's only the same a laying naked in the midday sun for 20~30 minutes.
For those wanting a general introduction watch
Vitamin D Prevents Cancer: Is It True?
Carole Baggerly does a very good job of summarising the situation.
For a more detailed look at the mechanics of how Vitamin D prevents/treats cancer then
How Vitamin D Reduces the Incidence of Cancer: The DINOMIT Model
and
Dose-Response of Vitamin D and a Mechanism for Cancer Prevention
provide more detailed scientific information. There are PDF files for those wanting to follow the research in even greater detail.
Kind regards,
Carmen
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