Tuesday Dec 3, 2013 (foodconsumer.org) -- A study in Journal of Physiology and Biochemistry shows that treatment with curcumin can reduce the formation of fetuin-A in rats eating a high fat diet.  Fetuin-A is linked to metabolic disorders such as visceral obesity, insulin resistance, diabetes mellitus and fatty liver.  Curcumin is known for its antioxidative, anticarcinogenic anti-inflammatory and hypoglycemic properties.  Curcumin treatment effectively reduced liver triglycerides and serum fetuin-A levels in rats on a high fat diet.  The study suggests that "the reduction of fetuin-A may contribute to the beneficial effects of curcumin in the pathogenesis of obesity."ReferenceOner-?yido?an Y, Koçak H, Seyidhano?lu M, Gürdöl F, Gülçubuk A, Yildirim F, Cevik A, Uysal M.  Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat diet.J Physiol Biochem. 2013 Dec;69(4):677-86. doi: 10.1007/s13105-013-0244-9. Epub 2013 Feb 22.