In a study in Cancer Research, sulforaphane, a compound in broccoli and its sprouts, stopped breast cancer stem cells from forming mammospheres at 7.5 uM. Mice given 50 mg/kg daily developed smaller tumors, most markedly when supplemented before receiving the cancer cells.
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Supplements
Dietary supplements: evidence, safety and new products.
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Supplements
Turmeric based herbal supplement as effective as antidiabetic drug
Diabetic rats given a 1:1 Curcuma longa and Eugenia jambolana supplement twice daily for six weeks had significantly lower fasting and random plasma glucose and 6% lower HbA1c than controls, an effect the researchers say matched the drug glibenclamide.
Supplements
Ketone supplements may fight advanced cancer
Mice with metastatic cancer on either a standard or ketogenic diet also received the ketone supplement 1,3-butanediol. The supplement slowed tumor growth and lengthened survival by 34 to 50 percent, and the researchers suggest it might help patients on standard care.
Supplements
Fenugreek extracts help treat drug resistant breast cancer
A 2016 study reports that fenugreek (Trigonella foenum) extract cut the viability, clonogenicity and invasion of doxorubicin-resistant breast cancer cells and made them more sensitive to the drug; in mice, the combination shrank tumors. The writer asks why the extract was not tested alone.
Supplements
Curcumin helps fight glioblastoma
Intranasal curcumin or its derivatives put 50% of treated mice with glioblastoma into remission, with similar results from an encapsulated form given intraperitoneally. A separate study suggests curcumin may suppress the cancer stem cells chemotherapy generates in pancreatic cancer.
Supplements
Nutritional therapy betters breast cancer outcomes
A study in Molecular Aspects of Medicine gave 32 high-risk breast cancer patients antioxidants, essential fatty acids and coenzyme Q10 alongside surgery and standard treatment. Over 18 months none died against four deaths expected, none showed new metastases, and six had partial remission.
Supplements
Beta-glucan lowers bad cholesterol
A review of 14 randomized trials in the FASEB Journal found that roughly 6.5 to 6.9 grams a day of barley beta-glucan, taken for about four weeks, moderately lowered LDL and non-HDL cholesterol compared with control diets, though it did not change apoB.
Supplements
Natural therapy better than chemotherapy at treating pancreatic cancer
A Cell Death and Disease study found gemcitabine killed pancreatic cancer cells but also induced drug resistance, while sulforaphane from cruciferous vegetables and quercetin killed the cells without inducing resistance. The work was done in cultured cells.
Supplements
Honokiol may help b-cell chronic lymphocytic leukemia
A study in Blood found honokiol, a compound from magnolia bark, roots and seed cones, killed B-cell chronic lymphocytic leukemia cells more readily than healthy cells and triggered caspase-mediated apoptosis. Clinical studies are still needed.
Supplements
Phellinus linteus may help some cancers
Laboratory studies of the medicinal mushroom Phellinus linteus show it can help relieve inflammation and may fight prostate, breast, colon, liver, lung, oral and skin cancers, but clinical trials are still needed to confirm any effect against these malignancies.
Supplements
Omega 3 fatty acids fight liver disease, cancer
In tumor-laden mice, omega-3 fatty acid supplements reversed steatosis caused by a high-fat diet, protected against ischemia reperfusion, improved liver regeneration and prolonged survival. The same benefits appeared in mice with lean livers.
Supplements
FDA MedWatch - GNC Women’s Ultra Mega Time Release 180 count Dietary Supplement by Nutra Manufacturing: Recall - Undeclared Milk
Nutra Manufacturing is recalling one lot of GNC Women's Ultra Mega Time Release, 180-count, lot 3044FQ2024, expiring June 2018, because it may contain undeclared milk. Buyers should check the lot number and return the bottle to a GNC store for a refund.
Supplements
Resveratrol supplements may fight ovarian cancer
In mice with implanted ovarian cancer cells, resveratrol cut tumor glucose uptake, and combined with cisplatin it significantly reduced cancer burden and suppressed regrowth compared with placebo. The authors report a significant antineoplastic effect in this preclinical model.
Supplements
Soy protein supplements benefit type 2 diabetes mellitus, metabolic syndrome
A 2015 review of randomized trials found soy protein supplementation significantly lowered fasting plasma glucose, fasting insulin, HOMA-IR, diastolic blood pressure, LDL and total cholesterol, and C-reactive protein in people with type 2 diabetes or metabolic syndrome.
Supplements
Mistletoe cancer treatment reviewed
A review reports that mistletoe therapy improves quality of life in cancer patients, and cites recent studies in which it raised the odds of surviving advanced pancreatic cancer and, at high doses, produced regression of several tumour types.
Supplements
Use of dietary supplements in U.S between 1999 and 2012
A survey of U.S. adults found multivitamin use fell from 37 percent in 1999-2000 to 31 percent in 2011-2012, while fish oil use rose from 1.3 percent to 12 percent and vitamin D supplementation apart from multivitamins rose from 5.1 percent to 19 percent.
Supplements
Soy protein helps men with diabetes mellitus
In 200 UK men with type 2 diabetes and low testosterone, 15 g of soy protein daily for three months left testosterone unchanged whether or not it contained isoflavones. The isoflavone version raised TSH, lowered free T4, and reduced HbA1c, HOMA-IR, triglycerides and CRP.
Supplements
Garcinia cambogia fights obesity, metabolic syndrome
An Indian review says hydroxycitric acid from Garcinia cambogia inhibited fat synthesis, suppressed appetite and cut body weight in earlier studies, with no adverse effects reported at up to 2,800 mg a day. The reviewers suggest it could be developed for obesity.
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