A meta-analysis of 10 observational studies found serum 25OHD concentrations 1.4 standard deviations lower in Alzheimer's patients than in matched healthy controls. The authors treat vitamin D as a possible biomarker of the disease rather than a proven cause.
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Other Diseases
Silicon rich mineral water helps Alzheimer's disease
Two reviews make the case that aluminum is a major Alzheimer's risk factor. One describes aluminum triggering reactive oxygen species and cutting ATP synthesis; the other argues chronic aluminum neurotoxicity is largely responsible in many cases, citing processed foods and alum-treated water.
Supplements
This ingredient found in meat helps Alzheimer's disease
Rats given homocystine to mimic Alzheimer's changes had less tau hyperphosphorylation and beta-amyloid accumulation and fewer memory deficits when fed acetyl-L-carnitine, a Rejuvenation Research study reports. The researchers call it a promising protective agent.
Herbs
Ancient Herb Proven to be a Potential Cure for Alzheimer's
Studies in mice suggest ashwagandha extract may reverse memory loss and improve cognition in Alzheimer's disease by boosting a liver protein that helps clear amyloid from the brain. Past research also points to the herb's antioxidant activity against brain cell damage.
Herbs
Curcumin fights Alzheimer's disease, Parkinson's disease
Michigan State researchers report in the Journal of Biological Chemistry that curcumin binds strongly to alpha-synuclein and prevents the protein clumping seen in Parkinson's and Alzheimer's disease at body temperature. They tracked protein folding using precise lasers.
Lifestyle
How Can Sunscreen Cause Alzheimer's?
Mercola argues that sunscreen blocks the skin from making both vitamin D and cholesterol sulfate, which he says may protect cells from glucose and oxygen damage. He presents this as a possible and little-discussed contributor to Alzheimer's risk.
Food
Red grape juice may help fight Alzheimer's disease
Rats given streptozotocin to induce Alzheimer's disease and then 10% red grape juice for 21 days had better memory and learning than untreated rats, an Iranian study reports. The writer notes falsified resveratrol research has cast doubt on that compound.
Drug
Green Light May Help Alzheimer’s Patients
Wayne State researchers gave light through visors to 20 women over 65 with Alzheimer's dementia. Caregivers reported that patients, most of them treated with green light, seemed more alert and showed better recall and coordination, while a few changed little or not at all.
Drug
No cure for Alzheimer's disease, but early diagnosis possible
In 140 people with mild memory impairment, Swedish researchers found low beta-amyloid and high tau in spinal fluid in 91% of those who developed Alzheimer's within ten years. They put the markers' accuracy near 90%, so clinical assessment is still needed.
Disease
Visceral fats may raise risk of Alzheimer's disease
Tufts researchers followed 840 volunteers averaging age 76 for about 13 years, during which 159 developed dementia, including 125 cases of Alzheimer's. They report that elevated adiponectin, a hormone from visceral fat, was associated with increased risk of dementia and Alzheimer's in women.
Vitamins
Diets high in Omega 3 fatty acid, vitamin B, C, D and E help prevent Alzheimer's disease
A study in Neurology found people with higher blood levels of omega-3 fatty acids and vitamins B, C, D and E were less likely to show the brain shrinkage tied to Alzheimer's and scored better on thinking and memory tests, while high trans fat diets tracked with the opposite.
Drug
Biomarkers May Be Used to Diagnose and Monitor Alzheimer’s More Effectively
Kaj Blennow of Gothenburg's Sahlgrenska Academy is developing new methods for diagnosing Alzheimer's and monitoring treatment, arguing that drugs aimed at clearing beta amyloid plaques have failed in major trials and that current mouse models link only tenuously to the common human form.
Food
Alzheimer’s Disease Risk Lower in Those Eating Baked, Broiled Fish
Among 260 cognitively healthy volunteers, those eating baked or broiled fish at least weekly showed better-preserved gray matter on MRI in brain areas at risk for Alzheimer's ten years later, and their five-year risk of decline to mild cognitive impairment or Alzheimer's fell to one-fifth of normal.
Vitamins
No cure for Alzheimer's disease? Try vitamin C!
A Journal of Biological Chemistry study of brain tissue from mice with Alzheimer's found vitamin C dissolved the toxic misfolded protein aggregates, as did dehydroascorbic acid, its oxidized form. The work was done on tissue in the lab, not in people.
Knowledgebase
Alzheimer's disease
An encyclopedia-style overview of the most common form of dementia, first described by Alois Alzheimer in 1906: usually diagnosed after 65, affecting 26.6 million people in 2006 and projected to reach 1 in 85 globally by 2050, with mean life expectancy after diagnosis of about seven years.
Disease
Alzheimer's disease linked to depression, diabetes and high blood pressure
A Lancet Neurology study led by Deborah Barnes found physical inactivity, depression, smoking, mid-life hypertension and obesity, low education and diabetes may account for up to 54 percent of US Alzheimer's cases. Barnes cautioned that the study does not prove these factors cause it.
Other Diseases
Green Tea helps fight Alzheimer's - new study
In cell tests, green tea's EGCG and a grape skin extract each cut amyloid-beta-triggered neurotoxicity by 40%, but only EGCG blocked amyloid fibril formation and aggregation, which the Adelaide researchers say is how it protects neural cells.
Food
Drinking green tea may help prevent Alzheimer's disease
Screening bioactive compounds, University of South Florida researchers found green tea's EGCG and luteolin most effective at correcting amyloid-induced mitochondrial dysfunction in vitro, and EGCG restored mitochondrial measures by 50 to 80% in several mouse brain regions.
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