Wednesday July 8, 2015 (foodconsumer.org) -- Drinking high fructose corn syrup (HFCS) sweetened beverages increases risk of cardiovascular disease, according to a study in the American Journal of Clinical Nutrition.

The study led by Kimber L Stanhope at the University of California in Davis, California, USA and colleagues showed drinking HFCS sweetened beverages significantly increased triglycerides, LDL cholesterol, and uric acid concentrations.  These risk factors are associated with cardiovascular disease.

In the current trial,  85 participants aged 18 to 40 years with body mass index ranging from18 to 35 kg/m2 were asked to consume beverages sweetened with HFCS at 0% (n = 23), 10% (n = 18), or 17.5% (n = 16), 25% (n = 28) for 13 days at home and 3.5 days at the research center.

The study found that drinking beverages with 10%, 17.5% or 25% of HFCS all led to an increase in postprandial triglycide, fasting LDL cholesterol, and 24-h mean uric acid concentrations in a dose-response matter.  This means, the more GFCS is consumed, the high the risk for cardiovascular disease.

The study concluded "These results provide mechanistic support for the epidemiologic evidence that the risk of cardiovascular mortality is positively associated with consumption of increasing amounts of added sugars."  The added sugar in the study is HFCS.

Data from the National Health and Nutrition Examination Survey as already shown an association between increased risk of cardiovascular disease mortality and increased intake of added sugar.  The current study revealed some details on what HFCS can do to increase the risk of caridovascular disease. (David Liu)

Kimber L Stanhope, Valentina Medici, Andrew A Bremer, Vivien Lee, Hazel D Lam, Marinelle V Nunez, Guoxia X Chen, Nancy L Keim, and Peter J Havel , A dose-response study of consuming high-fructose corn syrup–sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults, American Journal of Clinical Nutrition, 2015