A new study released in Cancer Research suggests that eating a high-fat diet may increase risk of lung cancer. The study shows that a high fat diet promoted tumorigenesis in two mouse models of lung cancer with K-ras mutations ,which were identified in about 25% cases of lung cancer. Researchers speculate that high fat diet promotes lung cancer by increasing systemic IGF-1, which is known to promote cancer growth. (David Liu)Jeffrey Norris, Krista Pearman, Regan Memmott, Kristin Lastwika, Joell Gills, Phillip Dennis. A high-fat diet promotes tumorigenesis in two mouse models of K-ras-driven lung cancer. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4330.
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High fat diet may raise lung cancer risk - study
A high-fat diet promoted tumor growth in two mouse models of K-ras-driven lung cancer, according to work presented at an AACR meeting. The researchers speculate the diet acts by raising systemic IGF-1; K-ras mutations appear in about 25 percent of human lung cancer cases.
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