Wednesday June 1, 2016 (foodconsumer.org) -- Co-presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 could drastically increase risk for high grade invasive breast cancer, according to a new study led by A. E. Al Moustafa at Syrian Research Cancer Centre of the Syrian Society against Cancer in Aleppo , Syria and colleagues.Al Moustafa et al. have previously found Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 present in human breast cancer diagnosed in Syrian men and women.The new study found 32% of 108 breast cancer samples were positive for both EBV and high-risk HPVs and co-presence of the two viruses was associated with high grade invasive breast cancer. In comparison, breast cancer found with only one type of virus was often low to intermediate grade tumors (ductal carcinomas).These studies suggest that women infected with both Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 could be at high risk for high grade invasive breast cancer and these viruses are risk factors for metastasis.Many viruses including some sexually transmitted viruses have been associated with increased risk for a variety of cancers including breast cancer and leukemia. (David Liu)Al Moustafa AE, Al-Antary N, Aboulkassim T, Akil N, Batist G, Yasmeen A. Co-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer. Hum Vaccin Immunother. 2016 Apr 15:1-4.Simialr studies
Incidence of Epstein-Barr virus in Syrian women with breast cancer: A tissue microarray study.
Review High-Risk HPVs and Human Carcinomas in the Syrian Population.
Review Epstein-Barr virus and breast cancer: state of the evidence for viral carcinogenesis.
Comments