Resveratrol helps type 2 diabetes mellitus

A meta-analysis covering 196 people with type 2 diabetes found resveratrol supplements significantly improved systolic blood pressure, HbA1c and creatinine, but not fasting glucose, insulin, insulin resistance, diastolic pressure, blood fats or cholesterol. Side effects matched placebo.

By Food Consumer · 2 min read

Monday Feb 16, 2015 (foodconsumer.org) -- A review in Molecular Nutrition & Food Research suggests that resveratrol, the red wine polyphenol can as an antioxidant help type 2 diabetes mellitus patients.Resveratrol has been found highly effective in treating type 2 diabetes mellitus (T2DM) in animal models. But the current review did not find the phytochemical as effective in human type 2 diabetes mellitus although it does affect some metabolic parameters.The meta-analysis of data from a total of 196 type 2 diabetes mellitus patients shows that supplementation with resveratrol renders a significant effect on systolic blood pressure, hemoglobin A1c and creatinine. Hemoglobin A1c is considered a reliable indicator for the severity of type 2 diabetes mellitus.Nevertheless, resveratrol supplementation does not significantly affect fasting glucose, homeostatic model assessment of insulin resistance, diastolic blood pressure, insulin concentrations, blood fat, low density lipoprotein cholesterol or high density lipoprotein cholesterol.In any case, no adverse effects were reported and side effects of resveratrol were found to be the same as those found with placebo or control.The authors say that "significant improvements in multiple cardiometabolic biomarkers and an excellent safety profile support resveratrol as a leading candidate as an adjunct to pharmacological management of T2DM (type 2 diabetes mellitus)."Another study published in 2013 in Evidence-Based Complementary and Alternative Medicine suggests that resveratrol found in red wine and red grapes can lower blood sugar in patients withtype 2 diabetes mellitus.Patients with type 2 diabetes mellitus who took resveratrol in a dose of 1 gram or 1000 mg per day for 45 days significantly not only decreased systolic blood pressure and hemoglobin A1c, but lowered fasting blood glucose, insulin and insulin resistance.Supplements that have been known to help diabetes mellitus patients or prevent the disease in the first place include curcumin (the key ingredient in turmeric), thiamine (a vitamin), cinnamon, vitamin d, Korean red ginseng (the best type of ginseng you can use), cholesterol-lowering statins, Kalpaamruthaa, green tea, amino acid called arginine, sesame seed paste and food proteins.Resveratrol may also help many other health conditions such as cancer, Alzheimer's disease, and obesity among others. Read on for more reports on resveratrol and its health benefits. (David Liu PHD)Heather A. Hausenblas, Jennifer A. Schoulda and James M. Smoliga, Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus—systematic review and meta-analysis, Issue Molecular Nutrition & Food Research, Molecular Nutrition & Food Research, Special Issue: Reviews Volume 59, Issue 1, pages 147–159, January 2015

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