Rutgers researchers genetically reduced the ATR enzyme in mice and found those animals developed UV-induced tumors more slowly, with 69 percent fewer tumors and four times fewer invasive ones. Caffeine inhibits ATR, which researchers say may explain its protective effect.
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Dining
Caffeine cravings may be brewing in your genes
A genome-wide study of 47,341 people of European descent found two loci tied to habitual caffeine intake, one near AHR and one between CYP1A1 and CYP1A2, genes involved in metabolizing caffeine. The authors report a large heritable component.
Chemical
Caffeine can't curb effects of alcohol
Adding caffeine to alcohol did not improve reaction time or driving-test performance among 129 people aged 21 to 30, a study in Addiction found. The authors see little or no protective benefit and call for scrutiny of how caffeinated alcoholic drinks are advertised.
Food
Don't use alcohol with energy drink
Regulators weighed action against caffeinated alcoholic drinks such as Four Loko after reports of illness and deaths. A study in Alcoholism found that adding an energy drink to alcohol dulled drinkers' sense of impairment without improving motor coordination or visual concentration.
Drug
Drinking Coffee May Cut Type 2 Diabetes Mellitus Risk
Among 1,141 American Indian adults with normal glucose tolerance followed 7.6 years, those drinking 12 or more cups of coffee a day had 67 percent lower risk of type 2 diabetes. A significant reduction showed up only at that level of consumption.
Other Diseases
Coffee health news: Caffeine drinking linked to less severe liver fibrosis
Among 177 chronic hepatitis C patients undergoing liver biopsy, those consuming about 308 mg of caffeine a day, roughly 2.25 cups of coffee, had milder fibrosis. Each extra 67 mg tracked with 14% lower odds of advanced fibrosis; caffeine from tea showed no such effect.
Dining
Alcohol should not be used in caffeine-laced energy drinks
The FDA wrote to about 30 makers of caffeinated alcoholic drinks, giving them 30 days to show that adding caffeine is generally recognised as safe or prior sanctioned, or face action to pull the products. Caffeine is approved in soft drinks up to 200 ppm but not in alcohol.
Legal Actions
FDA: Caffeine may not be used in alcoholic beverages
The FDA wrote to about 30 makers of caffeinated alcoholic drinks, giving them 30 days to show the caffeine is approved or generally recognized as safe, or face removal from the market. The agency says 26% of college students drink them.
Food
That Morning Cup of Ambition May Reverse Symptoms of Alzheimer’s
Fifty-five mice bred with Alzheimer's traits were split in two; after two months, those given caffeine in their water did better on thinking and memory tests than the water-only group. The University of South Florida researcher says it is the first work to suggest caffeine can undo damage.
Food
Caffeine before workouts may help moderate muscle pain
In a study of 25 college-aged men who cycled for 30 minutes, those given 5 mg of caffeine per kilogram of body weight reported a moderate reduction in quadriceps pain against placebo. The researcher says more work is needed beyond this group.
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