Among 1,150 patients with normal or near-normal liver and kidney function followed three years, those with non-alcoholic fatty liver diagnosed by ultrasound had significantly more cardiovascular events and renal impairment, and lower glomerular filtration rates.
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Disease
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Disease
Diabetes mellitus linked to bladder cancer in women
A meta-analysis of 10 case-control and 14 cohort studies links type 2 diabetes to about 30% higher bladder cancer risk overall and up to 23% higher risk in women, with no significant association in men. Case-control studies showed larger increases than cohort studies.
Disease
Testosterone therapy linked to death, myocardial infarction, and stroke ****
A JAMA study led by Rebecca Vigen found testosterone replacement therapy raised the risk of heart disease and related events like stroke and death by 29 percent. The piece notes US sales reached $1.6 billion in 2011 and that earlier trials detected no adverse cardiac events.
Disease
Vital Signs: Colorectal Cancer Screening Test Use — United States, 2012
In 2012, 65.1% of U.S. adults aged 50 to 75 were up to date with colorectal cancer screening and 27.7% had never been screened. The never-screened share reached 55.0% among people without insurance and 61.0% among those without a regular care provider.
Disease
PCRM Breaking Medical News: Genetic Connection to Diabetes Risk Overestimated
A review of 23 studies in the American Journal of Epidemiology concluded that genetic testing predicts type 2 diabetes risk less usefully than conventional factors such as weight, age and gender, though it may still have a place for some, perhaps younger populations.
Disease
HbA1c not good for diagnosis of type 2 diabetes mellitus
A BMC Public Health study led by Michael Lean found smoking linked to higher HbA1c in non-diabetics and high fruit and vegetable intake linked to lower levels, suggesting factors besides glucose move the marker and may limit how well it identifies type 2 diabetes.
Disease
Lack of Sleep May Increase Risk of Alzheimer’s Disease
Among 70 cognitively healthy adults aged 53 to 91 in the Baltimore Longitudinal Study of Aging, those reporting shorter sleep and difficulty falling asleep showed more of the plaques associated with Alzheimer's, according to a JAMA Neurology report.
Disease
Breast cancer and endometrial cancer, which is more dangerous?
Among 2,027 women in SEER data diagnosed with both breast and endometrial cancer, 63.9 percent developed breast cancer first. The cumulative five-year risk of death after the second diagnosis was nearly four times more likely to come from breast than endometrial cancer.
Disease
Human Form of “Mad Cow” Disease More Widespread Than Once Thought
Researchers tested 32,441 tissue samples from 41 British hospitals collected between 2000 and 2012 and found carriers of the prion protein linked to variant CJD at twice the rate of earlier surveys, with little variation by age, sex or region.
Disease
More Britons live with variant Creutzfeldt–Jakob disease
Researchers testing 32,000 appendix tissue samples from 41 UK hospitals estimate in the BMJ that as many as one in 2,000 Britons carry the abnormal prions behind variant Creutzfeldt-Jakob disease, well above an earlier estimate of about 3,000 people.
Disease
IGF-1 linked to poor breast cancer prognosis
Among 600 women with stage I-IIIA breast cancer, those in the highest quintile of serum IGF-1 were 210 percent more likely to die of any cause than those in the lowest, an International Journal of Cancer study reports. The IGF-1 to IGFBP-3 ratio showed a similar link.
Disease
Stress Linked to Alzheimer’s Disease
Researchers tracked 800 women in the Prospective Population Study of Women for 37 years and linked midlife psychosocial stressors such as divorce, a relative's illness and job loss to late-life dementia, especially Alzheimer's disease, in a BMJ Open study.
Disease
Younger women with type 2 diabetes face higher risk of heart disease (PR)
Carotid ultrasound in 1,256 Argentine women aged 19 to 84 found plaque more common among the 293 with type 2 diabetes than the 963 without, regardless of age, family history, smoking, blood pressure or menopausal status. The researchers urge screening diabetic women earlier.
Disease
Obesity, Diabetes boost breast cancer death risk
Researchers followed 1,607 Italian women diagnosed with breast cancer in 2003-2005 through 2008. Among those with ER+PR+ tumors, a higher BMI carried a 190% greater risk of dying of the disease and fasting glucose above 94 mg/dL a 160% greater risk.
Disease
The Surprising Disorder That Kills More People Worldwide Than AIDS, TB, Diabetes and Car Accidents
A Lancet analysis of 2010 Global Burden of Disease data from 187 countries found mental and substance use disorders were the leading cause of non-fatal illness worldwide, nearly 23% of the total disease burden, and the fifth leading cause of death and disease. Depressive disorders were most common.
Disease
Makes Viruses Grow Like Wildfire and Can Amplify Your Flu Symptoms
Mercola argues flu shots often fail, noting the well-matched 2012/13 vaccine was only slightly over 60% effective, and points to piglet research where vaccinating against one influenza strain raised the risk of severe infection with a related strain.
Disease
Diabetes type 2, induced abortion linked to breast cancer
An Armenian study of 302 women in Health Care for Women International found women with type 2 diabetes were nearly five times as likely to develop breast cancer. Induced abortion was tied to 186% higher risk and each year's delay in first pregnancy to 13%.
Disease
HIV infection promotes early kidney injury in women
Women with HIV had higher urine levels of the kidney injury markers IL-18 and KIM-1, and higher ACR, than uninfected women, in a comparison of 908 infected women and 289 controls from the Women's Interagency HIV Study published in Antiviral Therapy.
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