In a JAMA study of out-of-hospital cardiac arrest, 13.3% of patients who received compression-only CPR from bystanders survived to hospital discharge, against 7.8% for conventional CPR and 5.2% for those who got no CPR.
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Drug
Prescription drugs, vaccines and their risks and benefits.
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Drug
Finally, the FDA Decides to Curb Avandia – But Did the Agency Go Far Enough?
FDA will restrict Avandia through a Risk Evaluation and Mitigation Strategy, limiting new patients to those who cannot control blood sugar otherwise. Mercola notes British regulators went further, telling 90,000 patients to stop taking the diabetes drug.
Drug
Pink News: Mammogram Screening Works for Women Ages 40-49
A Swedish study in Cancer compared women aged 40 to 49 invited to mammography screening with those who were not, between 1986 and 2005, and found fewer breast cancer deaths among those screened. An editor's note calls screening in this age group a contested question among experts.
Drug
Electroconvulsive therapy recommended for major depression
The American Psychiatric Association's first depression guideline update since 2000 lists electroconvulsive therapy for major depressive disorder in patients with severe symptoms or no response to medication, and adds transcranial magnetic stimulation and vagus nerve stimulation.
Drug
Deadlier than AIDS: Why is This Travesty Allowed to Continue in the U.S.?
Mercola argues that antibiotic overuse drives resistance, noting some 70 percent of American antibiotics go into animal feed and that the EU banned the practice years ago. He says resistant infections now claim more lives yearly than AIDS and cost about $20 billion.
Drug
Prostate cancer patients may become impotent after surgery
A Spanish review found erectile dysfunction after prostate cancer surgery varied by technique: 22 percent with robotic surgery, 40 percent with laparoscopic and 41.4 percent with open radical prostatectomy. The underlying case series were rated low quality.
Drug
FDA: Risky diabetes drug Avandia should stay
The FDA will keep Avandia on the market but limit it to type 2 diabetes patients who cannot control the disease on other drugs. Agency reviewers David Graham and Thomas Marciniak, and cardiologist Steven Nissen, had urged a ban, calling the rival drug Actos safer.
Drug
Mammograms not effective as thought - new study
A Norwegian study following 40,075 women from 1996 through 2005 attributes only about a 10 percent reduction in breast cancer deaths to screening, or 2.4 fewer deaths per 100,000 person-years. Danish work put the benefit lower still, and the findings ran in NEJM.
Drug
Breast cancer treatment causes sexual dysfunction
A survey of 1,700 breast cancer survivors found 70 percent of partnered women aged 70 or under with no active disease reported sexual function problems two years after diagnosis, though more than 80 percent described a satisfying sex life beforehand. Body image and endocrine therapy featured.
Drug
Nearly 30,000 Americans Get Cancer From This One Procedure EVERY Year: Will You?
CT scans give higher-resolution images than ordinary X-rays but expose patients to hundreds or thousands of times the radiation. US use rose from about 3 million scans in 1980 to over 70 million a year. An Archives of Internal Medicine study estimated they cause nearly 30,000 cancers a year.
Drug
Hormone therapy raises breast cancer risk - study
A study in the Journal of the National Cancer Institute ties falling hormone replacement therapy use to a drop in Canadian breast cancer incidence from 296 to about 278 cases per 100,000 women between 2002 and 2004. The study was observational, though the authors call the link likely causal.
Drug
This "Miracle Drug" Could Nearly Double Your Risk of Cancer
A BMJ analysis comparing thousands of cancer patients with matched controls found long-term users of oral bisphosphonates such as Fosamax, Actonel and Boniva had close to double the risk of esophageal cancer. An earlier FDA report had cited cases among Fosamax users in the US, Europe and Japan.
Drug
High-doses Aspirin relieves headache, migraine effectively
A Neurology study of 168 patients found intravenous high-dose aspirin cut pain 30 percent about a quarter of the time in people hospitalized for severe headache and migraine tied to drug withdrawal. UCSF says IV aspirin can cost $7 a dose against $22 a pill for triptans.
Drug
Aromatase Inhibitors in Products Marketed as Dietary Supplements: Recall
The FDA warns that products sold as dietary supplements contain aromatase inhibitors known as ATD, which it says are not dietary ingredients. Listed harms include reduced sperm production, infertility, aggression, kidney failure and liver dysfunction.
Drug
Get Your Flu Vaccine: Stay Healthy This Flu Season!
CDC recommends flu vaccination for everyone 6 months and older, plus hand washing, staying home when sick, and antiviral drugs when a doctor prescribes them. Each season 5% to 20% of Americans get flu and more than 200,000 land in hospital with complications.
Drug
Diabetes drug Actos linked to bladder cancer
The FDA said long-term use of pioglitazone was associated with a raised risk of bladder cancer in people with type 2 diabetes, citing animal studies and two three-year trials. It has not concluded the drug causes the risk and told patients not to stop taking it.
Drug
Kidney cancer drug Votrient may help some thyroid cancer
In a phase II trial of 37 patients with rapidly progressing thyroid cancer, 49 percent saw their tumour mass shrink on pazopanib, and 73 percent of those with follicular disease responded. Side effects forced dose reductions in 15 patients, and two patients died during treatment.
Drug
FDA okays three defibrillators to treat heart failure
FDA approved three Boston Scientific cardiac resynchronization defibrillators for heart failure patients with left bundle branch block. In a three-year trial of 1,820 patients, those with the block had 57 percent lower risk of death and heart failure than with a defibrillator alone.
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