UC Davis researchers found more than a dozen immune targets shared by the 2009 H1N1 virus and seasonal flu strains, which they say may explain why many people over 60 carry antibodies and why symptoms were generally mild. They suggest cell-mediated immunity does the work.
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H1N1
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Drug
People Who Get a Seasonal Flu Shot Are Twice as Likely to Catch Swine Flu
Unpublished Canadian data, still in peer review, suggests people who got last year's seasonal flu shot were about twice as likely to catch swine flu. The post also lists the five companies awarded U.S. contracts for more than 195 million doses of swine flu vaccine.
Vitamins
Vitamin D protects against H1N1 - new evidence
Vitamin D Council president John Cannell circulates a physician's account of a June 2009 H1N1 outbreak at a Wisconsin care facility, where two of about 275 vitamin D-supplemented residents fell ill against roughly 60 of 800 staff, and urges readers to contact their representatives in Washington.
Drug
Ancient Chinese remedy may help stop swine flu
Researchers at Kaohsiung Medical University in Taiwan tested roots of Ferula asafetida, used against the 1918 influenza pandemic, and found some of its compounds killed H1N1 virus as potently as a prescription antiviral. They say the finding may aid new drug development.
Phytochemicals
Elderberry fruit extract may help fight H1N1 flu
In lab tests, an elderberry fruit extract blocked H1N1 infection at an IC50 of 252 micrograms/mL, with its flavonoids binding directly to virions. Two compounds the researchers synthesised inhibited the virus at concentrations they call comparable to Tamiflu and amantadine.
Disease
2008-2009 Influenza Season Week 35 ending September 5, 2009
CDC surveillance for the week ending September 5, 2009: 20.5% of specimens tested positive for influenza, 97% of subtyped A viruses were 2009 H1N1, one pediatric death was reported, and eleven states plus Guam saw widespread activity.
Disease
H1N1 in Chicago
Chicago's health department confirmed 1,557 cases between April 24 and July 25, 2009. The attack rate was highest in children aged 5 to 14, fourteen times the rate for adults 60 and older, and 13% of patients were hospitalized, supporting vaccination aimed at the young.
Vitamins
Canada Looks at Vitamin D for Swine Flu Protection
The Public Health Agency of Canada confirmed it will adapt an existing study of vitamin D and severe seasonal influenza to the H1N1 virus, partly to learn whether vitamin D levels explain why most flu cases stay mild. Dr. Mercola urges readers not to wait for the results.
Disease
CDC: 302 Americans with H1N1 have died so far
CDC reported 302 U.S. deaths and 43,771 confirmed or probable H1N1 cases since March 2009. The piece notes one official's estimate that more than a million Americans may have been infected without knowing, which would put mortality closer to one death per 3,300 people.
Disease
Obese people at risk of severe complications and death from H1N1 infection
An editor's note frames a verbatim CDC report on Michigan intensive-care patients with the novel H1N1 virus, predicting officials will urge obese people to get vaccinated and calling that good business for drug makers. The CDC counted 94,512 cases and 429 deaths worldwide as of July 6, 2009.
Disease
Real-time science needed to stop new flu virus
IOM president Harvey Fineberg writes in Science that the 1976 Fort Dix response, a mass vaccination followed by more than 500 Guillain-Barre cases and 30 deaths, shows decision makers must ask what added information would change their course, and ask it while an epidemic unfolds.
Disease
Swine flu: What you need to know
A question-and-answer primer on the 2009 H1N1 virus: where it was first detected, why it was called swine flu, how its quadruple reassortant genes differ from viruses circulating in North American pigs, and which symptoms it shares with seasonal flu.
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