Chinese researchers fed 40 young male rats a common or high-fat diet for 16 weeks. All three high-fat diets raised body weight significantly, but rats given equal amounts of omega-3 and omega-6 fats kept insulin sensitivity close to controls and had lower pro-inflammatory cytokines.
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High-Fat Diet
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Diet
High fat diet gets you colon cancer - studies
Mice inoculated with colon cancer cells and fed a diet with 60% of calories from fat grew larger tumors and more lung tumors while gaining only 5.9% body weight, Korean researchers report. Insulin and IGF-I, both cancer promoters, also rose.
Autoimmune Diseases
Lupus patients should avoid high fat diet
Lupus-prone mice fed a high-fat diet for 14 weeks developed albuminuria far more often than controls, 57 percent against 20 percent, and showed impaired carotid artery relaxation and more ovarian fat. The authors say such a diet would raise cardiovascular risk in lupus.
Heart & Blood
High fat low carb diet may raise heart risk
In an 8-week trial of 24 overweight and obese adults, a 60 percent fat, 20 percent carbohydrate diet matched a low-fat, high-carb diet on weight loss and glucose metabolism, but researchers concluded its heart disease risks outweighed the benefits.
Food
High fat diet impairs memory and physical performance
Rats fed a high-fat diet for nine days did worse on maze and treadmill tests than rats on a low-fat diet, a British study published by FASEB found. Cambridge physiologist Andrew Murray was cited as finding similar effects in people, but those results are unpublished.
Diet
Fatty diet linked to high risk of pancreatic cancer
Among more than 500,000 adults in the NIH-AARP study followed about 6.3 years, those eating the most saturated fat were 36 percent more likely to develop pancreatic cancer, rising to 43 percent for saturated fat from animal sources.
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