Following 126,293 adults for more than 20 years, Kaiser Permanente researchers found smoking the strongest predictor of lung cancer, then heavy drinking of more than three drinks a day, with beer showing the strongest effect. A Czech study tied black tea and fruit to lower risk.
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Vitamins
Vitamin C, vitamin D may help fight lung cancer
Taiwanese researchers implanted Lewis lung carcinoma in mice, then injected vitamin C and vitamin D combinations twice weekly for 28 days. They report dose-dependent suppression of tumour growth and spread, normalised body weight and lower plasma metalloproteinase activity.
Vitamins
Not all types of vitamin E fight lung cancer
Rutgers researchers fed mice carrying transplanted lung cancer cells diets with different tocopherols and found delta-tocopherol inhibited tumor growth most strongly, gamma-tocopherol less so, and alpha-tocopherol not at all. Delta also cut oxidative DNA damage and promoted tumor cell death.
Food
Red meat also linked to higher risk of lung cancer
A study in the Asian Pacific Journal of Cancer Prevention comparing 876 men with lung cancer to 766 controls found fried, barbecued and salted red meat linked to higher risk, salted most of all, while broiled meat looked protective. Britain separately capped advice at 500 g a week.
Lifestyle
Passive smoking causes more heart disease deaths than lung cancer deaths
WHO researchers estimate secondhand smoke kills about 600,000 people a year worldwide, including 379,000 from heart disease and 21,400 from lung cancer. Two-thirds of those deaths occur in Africa and south Asia, and about 165,000 are children.
Disease
Rates of New Lung Cancer Cases in the US
In 2006, doctors told 106,374 U.S. men and 90,080 women they had lung cancer — 82.7 and 55.0 cases per 100,000. Smoking is blamed for about 90 percent of cases in men and nearly 80 percent in women. Black men had the highest incidence, white women the most new cases.
Disease
November is Lung Cancer Awareness Month
November marks a national campaign on lung cancer, the leading cause of cancer death in US men and women. Nearly 200,000 people are diagnosed each year and more than 90,000 die. Smoking causes 80 to 90 percent of cases; radon and asbestos are also listed as risks.
Environment
Wood dust exposure may boost lung cancer risk
Fred Hutchinson researchers compared 440 lung cancer cases with 845 matched controls and found sawmill workers were 50 percent more likely to develop lung cancer. They reported no raised risk from other occupations, woodworking as a hobby, or estimated cumulative wood dust exposure.
Drug
Spiral CT cuts risk of death from lung cancer?
A National Cancer Institute-funded study in Radiology found heavy smokers screened with low-dose spiral CT were 20 percent less likely to die of lung cancer than those screened with chest X-rays. Most earlier trials, including an Italian study of 2,472 men, found no such benefit.
Drug
Many physicians don't follow guidelines about lung cancer screening
A National Cancer Institute survey of 962 primary care physicians found two-thirds thought spiral CT screening cuts lung cancer deaths in smokers and 67 percent would recommend screening asymptomatic patients, though the authors say no guideline or high-quality study supports it.
Drug
Spiral CT cuts lung cancer death risk in heavy smokers
In an NCI-funded trial of more than 53,000 smokers aged 55 to 74, those screened with low-dose spiral CT were 20 percent less likely to die of lung cancer than those given chest x-rays, with 354 lung cancer deaths versus 442. All-cause mortality was 7 percent lower.
Environment
Diesel motor exhaust boosts lung cancer risk
Pooling 11 European and Canadian case-control studies covering 13,304 lung cancer cases and 16,282 controls, Karolinska researchers found workers with the heaviest cumulative diesel exhaust exposure were up to 31 percent more likely to be diagnosed with lung cancer than the least exposed.
Supplements
The cure for lung cancer may be in fish oil
A University of Nevada case report describes a 78-year-old man with terminal lung cancer who refused radiotherapy and chemotherapy, took 15 grams of DHA and EPA a day and avoided linoleic acid. His tumours shrank and disappeared, and he was alive five years later.
Vitamins
B vitamins may help prevent cancer
In Cancer Epidemiology, Biomarkers & Prevention, the highest serum vitamin B2 and B6 levels were tied to 29 and 32 percent lower colorectal cancer risk, with no effect from B12. A separate EPIC analysis linked B6, methionine and folate to lower lung cancer risk.
Lifestyle
Passive smoking more harmful than thought
Weill Cornell researchers measured nicotine and cotinine in 121 people and scanned their airway cells, finding that any detectable level, from passive or infrequent smoking, correlated with abnormal activity in genes tied to lung disease. The study appeared in AJRCCM.
Food
Soy foods help prevent lung cancer in non-smokers
Among 76,661 Japanese adults followed 11 years, never-smoking men in the top quarter for isoflavone intake were 57 percent less likely to be diagnosed with lung cancer, with a similar pattern in never-smoking women. Current and former smokers showed no such link.
Cancer
Cancer News: Green Tea Prevents Lung Cancer
A Taiwanese case-control study comparing 170 lung cancer patients with 340 healthy people found that drinking at least one cup of green tea a day was associated with sharply lower lung cancer risk among both smokers and non-smokers, with growth factor genotypes also shaping the risk.
Drug
FDA rejects Traceva for earlier use in lung cancer patients
An FDA panel rejected Tarceva as maintenance treatment for advanced lung cancer patients who have finished chemotherapy. In a study of 889 such patients, median progression-free survival was 12.3 weeks on Tarceva against 11.1 weeks on placebo.
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