The FDA approved Botox for chronic migraine, though a phase 3 trial found patients on it went headache-free 9 of 28 days versus 6.7 on placebo. Studies tying obesity to migraine suggest losing weight may also help manage the condition.
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Drug
FDA Okays Anti-wrinkle Botox for Migraine Headache
The FDA approved Botox injections on October 14 to prevent headaches in adults with chronic migraine, defined as headache on more than 14 days a month. An FDA neurology official called chronic migraine one of the most disabling forms of headache.
Miscellaneous
Intravenous Aspirin for Migraine Pain Relief?
Researchers reviewed records of 168 London patients hospitalized for chronic daily headache who received an average of five doses of intravenous aspirin, and reported reduced pain. Co-author Peter Goadsby says IV delivery may help more intense headaches.
Sci-Tech
Will Migraine Gene Discovery Provide Pain Relief?
Comparing the genomes of more than 3,000 Europeans who get migraines with 10,000 who do not, researchers report in Nature Genetics that a variant on chromosome 8, between genes that help control the brain chemical glutamate, is significantly more common in migraine sufferers.
Disease
Migraine linked to elevated cardiovascular risk
Albert Einstein College of Medicine researchers compared 6,102 people with migraine to 5,243 without and found heart attacks in 4.1 versus 1.9 percent. Migraine with aura carried triple the risk, and migraine sufferers more often had diabetes, hypertension and high cholesterol.
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