Wake Forest researchers found socially stressed monkeys secreted more cortisol and carried more visceral fat than calmer ones, even at matching weight and BMI. Stressed females put on belly fat as readily as males, losing their usual relative protection from plaque buildup.
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Health News
Drugs, disease, healthcare, government and lifestyle: health news beyond the plate.
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Drug
FDA: Celltep raises severe anemia risk
The FDA now requires a warning that the kidney transplant drug can cause pure red cell aplasia, a severe anemia marked by extreme fatigue and pallor. The agency already required notice of infection risk and strongly discourages use during pregnancy.
Disease
2008-2009 Influenza Season Week 31 ending August 8, 2009
CDC surveillance for August 2-8, 2009: influenza activity decreased slightly but influenza-like illness stayed above normal for the season. A total of 7,511 hospitalizations and 477 deaths from novel H1N1 had been reported, and H1N1 made up 98 percent of subtyped influenza A viruses.
Drug
New chemical attacks tumor-fueling cancer cells
Whitehead and Broad Institute researchers report in Cell that salinomycin kills breast cancer stem cells, cutting their number more than 100-fold compared with paclitaxel and shrinking tumors in mice. Such cells resist current therapies and are thought to seed new tumors.
Drug
FDA Approves Drug for Shizophrenia and Bi-Polar Disorder
The FDA has approved a Schering-Plough drug for schizophrenia and bipolar 1 disorder, due on the US market in the fourth quarter with a black box warning. Side effects run from sedation and weight gain to a higher death risk in dementia-related psychosis. One patient plans to try it.
Disease
Cancer deaths -- even in the young -- drop dramatically
Research in Cancer Research reports that U.S. cancer death rates have fallen since the early 1950s, with the steepest declines among adults aged 35 to 45. Each decade of births from 1925 to 1995 faced lower risk than the one before at nearly every age; lung cancer was the exception.
Drug
Aspirin Blocks Recurrence of Colorectal Cancer
Among 1,279 people with non-metastatic colorectal cancer followed about 12 years, those taking aspirin before and after diagnosis were a third less likely to die of it, and those who started only after diagnosis fared better still. Aspirin inhibits COX-2, an enzyme found in these tumours.
Disease
Inherited blindness treatable via gene therapy
A year after corrective RPE65 genes were delivered to small areas of their retinas, three adults aged 21 to 42 born with Leber congenital amaurosis type 2 had far better vision, and their brains adapted to use the treated regions, University of Florida researchers report.
Government
FDA Lessens Drug Restriction for Dying Patients
The FDA launched a website explaining expanded access, or compassionate use, for patients with serious or life-threatening illness who are ineligible for clinical trials. Requests go case by case, and the drug's maker must agree and work with the patient's physician.
Drug
Antidepressants raise suicide risk in young people
An FDA-led review of 372 trials covering nearly 100,000 adults found antidepressants raised suicide risk in people under 25 while lowering it in those 65 and older, Reuters reported. The analysis appeared on the British Medical Journal website.
Disease
Arkansas reports first swine flu death
The Arkansas Department of Health reported the state's first death from H1N1 complications and withheld further details for confidentiality. The CDC listed 11 states with regional flu activity, and the WHO counted 162,380 lab-confirmed cases and 1,154 deaths worldwide as of Aug. 4.
Environment
Radiation raises diabetes risk in cancer survivors
An Archives of Internal Medicine study compared 8,599 childhood cancer survivors with 2,936 siblings and found 2.5 percent had diabetes against 1.7 percent. Abdominal radiation raised the odds 2.7-fold and total body radiation 7.2-fold, unrelated to BMI or activity.
Environment
Antibiotic Resistant Staph: A Threat to Home HealthCare Providers
Archives of Internal Medicine reports 191 of 1,501 patients screened on leaving hospital carried methicillin-resistant staph, and 36 picked it up during follow-up. Home caregivers face the greatest risk, since staph spreads by skin contact and through used bandages and towels.
Miscellaneous
Young Women Look to Their Own Mothers for Parenting Advice
An Ohio State study of 1,133 young parents whose own parents took a 1979 survey found women more likely than men to copy their mother's approach to reading, spanking and praising. Co-author Jonathon Vespa notes practices shifted too, with 1990s parents less likely to spank.
Lifestyle
Breastfeeding linked to lower breast cancer risk
A study in the Archives of Internal Medicine links breastfeeding to a 59 percent lower breast cancer risk among women whose mother or sister had the disease. The piece also notes reported reductions in type 2 diabetes, ovarian cancer and rheumatoid arthritis risk.
Lifestyle
Breastfeeding reduces breast cancer risk
Among 60,075 women in the Nurses' Health Study II, breastfeeding showed no overall link to premenopausal breast cancer. But women whose mother or sister had the disease were 59 percent less likely to develop it before menopause if they breastfed.
Lifestyle
Optimists live longer, healthier lives, study shows
In an eight-year University of Pittsburgh study of nearly 100,000 post-menopausal women, the most optimistic had a 9% lower risk of heart disease and a 14% lower risk of dying from any cause, while the most hostile and cynical were 16% more likely to die.
Miscellaneous
Border collies: "Super dogs" of the species
Dog expert Stanley Coren told the American Psychological Association that dogs understand more than 150 words and reason roughly like a two-year-old, and that super dogs in the top 20 percent learn 250. The writer punctuates each claim with his own dog's less impressive habits.
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